Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This r...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2018-06-01
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| Series: | Journal of Dentistry |
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| Online Access: | http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1696/1125 |
| _version_ | 1818292291021832192 |
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| author | Saede Atarbashi-Moghadam Ali Lotfi Shokoufeh Shahrabi-Farahani Fazele Atarbashi-Moghadam |
| author_facet | Saede Atarbashi-Moghadam Ali Lotfi Shokoufeh Shahrabi-Farahani Fazele Atarbashi-Moghadam |
| author_sort | Saede Atarbashi-Moghadam |
| collection | DOAJ |
| description | Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This report presents a 4-year-old male patient with a rapidly growing mandibular gingival mass with some evidence of underlying alveolar bone destruction. Incisional biopsy was performed and the specimen was stained with hematoxylin and eosin and immunohistochemical antibodies for αSMA, CD34, S100 and desmin. The diagnosis of myofibroma was made and the lesion was completely excised. The knowledge about microscopic features of this rare neoplasm helps to have a proper diagnosis and avoid unnecessary treatment. |
| first_indexed | 2024-12-13T02:57:37Z |
| format | Article |
| id | doaj.art-2fd6057ac8774afd897ec9196d7c9ad8 |
| institution | Directory Open Access Journal |
| issn | 2345-6485 2345-6418 |
| language | English |
| last_indexed | 2024-12-13T02:57:37Z |
| publishDate | 2018-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dentistry |
| spelling | doaj.art-2fd6057ac8774afd897ec9196d7c9ad82022-12-22T00:01:54ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182018-06-01192164167Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case ReportSaede Atarbashi-Moghadam 0Ali Lotfi 1Shokoufeh Shahrabi-Farahani 2Fazele Atarbashi-Moghadam 3Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Division of Oral and Maxillofacial Pathology, Dept. of Diagnostic Sciences and Oral Medicine, University of Tennessee Health Science Center, College of Dentistry, Memphis, TN.Dept. of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This report presents a 4-year-old male patient with a rapidly growing mandibular gingival mass with some evidence of underlying alveolar bone destruction. Incisional biopsy was performed and the specimen was stained with hematoxylin and eosin and immunohistochemical antibodies for αSMA, CD34, S100 and desmin. The diagnosis of myofibroma was made and the lesion was completely excised. The knowledge about microscopic features of this rare neoplasm helps to have a proper diagnosis and avoid unnecessary treatment.http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1696/1125MyofibromaSmooth Muscle ActinGingivaImmunohistochemistrySoft Tissue Neoplasms |
| spellingShingle | Saede Atarbashi-Moghadam Ali Lotfi Shokoufeh Shahrabi-Farahani Fazele Atarbashi-Moghadam Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report Journal of Dentistry Myofibroma Smooth Muscle Actin Gingiva Immunohistochemistry Soft Tissue Neoplasms |
| title | Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report |
| title_full | Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report |
| title_fullStr | Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report |
| title_full_unstemmed | Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report |
| title_short | Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report |
| title_sort | myofibroma as a rapidly growing gingival mass in a 4 year old boy a case report |
| topic | Myofibroma Smooth Muscle Actin Gingiva Immunohistochemistry Soft Tissue Neoplasms |
| url | http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1696/1125 |
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