Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia
INTRODUCTION: Urinary tract infections (UTIs) remain among significant causes of morbidity and mortality in pregnant women in sub-Saharan Africa. Zambia shares this burden disproportionately compared to other countries and it is unknown to what extent HIV affects UTIs. This study investigated the pr...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2020-12-01
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| Series: | The Pan African Medical Journal |
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https://www.panafrican-med-journal.com/content/article/37/328/pdf/328.pdf
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| _version_ | 1818910165970190336 |
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| author | Moses Mukosha Lukundo Nambela Chiluba Mwila Micheal Chigunta Aubrey Chichonyi Kalungia Mwansa Ketty Lubeya Bellington Vwalika |
| author_facet | Moses Mukosha Lukundo Nambela Chiluba Mwila Micheal Chigunta Aubrey Chichonyi Kalungia Mwansa Ketty Lubeya Bellington Vwalika |
| author_sort | Moses Mukosha |
| collection | DOAJ |
| description | INTRODUCTION: Urinary tract infections (UTIs) remain among significant causes of morbidity and mortality in pregnant women in sub-Saharan Africa. Zambia shares this burden disproportionately compared to other countries and it is unknown to what extent HIV affects UTIs. This study investigated the prevalence of UTIs and associated factors among HIV infected pregnant women attending antenatal care at a tertiary hospital in Zambia. METHODS: we conducted a retrospective review of medical records of Zambian HIV infected pregnant women who attended antenatal care at the women and newborn hospital between 1st January 2017 and 31stDecember 2017. We used a structured data extraction tool to extract data from the patient medical records using simple random sampling without replacement. Medical records of patients with known, diabetes and renal transplant were excluded. A logistic regression model was used to establish factors associated with UTIs. RESULTS: we reviewed 380 medical records of pregnant women with a median age of 29 years (IQR: 22, 34). UTIs prevalence was 16.5%, (95% CI: 13.0, 20.7). Women with UTIs had lower gestational age than those without UTI (difference 3 weeks, P=0.0001). Gestational age was independently associated with UTI (AOR: 0.96, 95% Cl: 0.91-0.99). CONCLUSION: the burden of UTIs in this population was high compared to global estimates and gestational age predicts UTIs. Public health interventions should be directed at promoting an early screening of UTIs during pregnancy, preferably to educate HIV positive women to book for antenatal early so that screening could commence. |
| first_indexed | 2024-12-19T22:38:29Z |
| format | Article |
| id | doaj.art-2fd63d276867439d86e623f3012ccb7d |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-19T22:38:29Z |
| publishDate | 2020-12-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-2fd63d276867439d86e623f3012ccb7d2022-12-21T20:03:08ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882020-12-013732810.11604/pamj.2020.37.328.2024520245Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, ZambiaMoses Mukosha0Lukundo Nambela1Chiluba Mwila2Micheal Chigunta3Aubrey Chichonyi Kalungia4Mwansa Ketty Lubeya5Bellington Vwalika6 Department of Pharmacy, The University of Zambia, Lusaka, Zambia Faculty of Pharmacy Nutrition and Dietetics, Apex Medical University, Lusaka, Zambia Department of Pharmacy, The University of Zambia, Lusaka, Zambia Faculty of Pharmacy Nutrition and Dietetics, Apex Medical University, Lusaka, Zambia Department of Pharmacy, The University of Zambia, Lusaka, Zambia Department of Obstetrics and Gynecology, The University of Zambia, Lusaka, Zambia Department of Obstetrics and Gynecology, The University of Zambia, Lusaka, Zambia INTRODUCTION: Urinary tract infections (UTIs) remain among significant causes of morbidity and mortality in pregnant women in sub-Saharan Africa. Zambia shares this burden disproportionately compared to other countries and it is unknown to what extent HIV affects UTIs. This study investigated the prevalence of UTIs and associated factors among HIV infected pregnant women attending antenatal care at a tertiary hospital in Zambia. METHODS: we conducted a retrospective review of medical records of Zambian HIV infected pregnant women who attended antenatal care at the women and newborn hospital between 1st January 2017 and 31stDecember 2017. We used a structured data extraction tool to extract data from the patient medical records using simple random sampling without replacement. Medical records of patients with known, diabetes and renal transplant were excluded. A logistic regression model was used to establish factors associated with UTIs. RESULTS: we reviewed 380 medical records of pregnant women with a median age of 29 years (IQR: 22, 34). UTIs prevalence was 16.5%, (95% CI: 13.0, 20.7). Women with UTIs had lower gestational age than those without UTI (difference 3 weeks, P=0.0001). Gestational age was independently associated with UTI (AOR: 0.96, 95% Cl: 0.91-0.99). CONCLUSION: the burden of UTIs in this population was high compared to global estimates and gestational age predicts UTIs. Public health interventions should be directed at promoting an early screening of UTIs during pregnancy, preferably to educate HIV positive women to book for antenatal early so that screening could commence. https://www.panafrican-med-journal.com/content/article/37/328/pdf/328.pdf urinary tract infectionzambiaprevalencehivpregnancygestational agebookingantenatal careasymptomatic bacteriuria |
| spellingShingle | Moses Mukosha Lukundo Nambela Chiluba Mwila Micheal Chigunta Aubrey Chichonyi Kalungia Mwansa Ketty Lubeya Bellington Vwalika Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia The Pan African Medical Journal urinary tract infection zambia prevalence hiv pregnancy gestational age booking antenatal care asymptomatic bacteriuria |
| title | Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia |
| title_full | Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia |
| title_fullStr | Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia |
| title_full_unstemmed | Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia |
| title_short | Urinary tract infections and associated factors in HIV infected pregnant women at a tertiary hospital in Lusaka, Zambia |
| title_sort | urinary tract infections and associated factors in hiv infected pregnant women at a tertiary hospital in lusaka zambia |
| topic | urinary tract infection zambia prevalence hiv pregnancy gestational age booking antenatal care asymptomatic bacteriuria |
| url |
https://www.panafrican-med-journal.com/content/article/37/328/pdf/328.pdf
|
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