Aerosol prime-boost vaccination provides strong protection in outbred rabbits against virulent type A Francisella tularensis.
Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by the gram-negative bacterium Francisella tularensis (Ft). While there have been a number of attempts to develop a vaccine for Ft, few candidates have advanced beyond experiments in inbred mice. We report here that...
Main Authors: | Katherine J O'Malley, Jennifer D Bowling, Elizabeth Stinson, Kelly S Cole, Barbara J Mann, Prachi Namjoshi, Karsten R O Hazlett, Eileen M Barry, Douglas S Reed |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6197691?pdf=render |
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