Inducing Ectopic T Cell Clusters Using Stromal Vascular Fraction Spheroid‐Based Immunotherapy to Enhance Anti‐Tumor Immunity

Inducing Ectopic T Cell Clusters Using Stromal Vascular Fraction Spheroid‐Based Immunotherapy to Enhance Anti‐Tumor Immunity

Abstract Tertiary lymphoid structures (TLSs) provide specialized niches for immune cells, resulting in improved prognoses for patients undergoing cancer immunotherapy. Shaping TLS‐like niches may improve anti‐cancer immunity and overcome the current limitations of immune cell‐based immunotherapy. He...

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Bibliographic Details
Main Authors: Jae‐Won Lee, Bum Chul Park, Na Yoon Jang, Sihyeon Lee, Young Kyu Cho, Prashant Sharma, Sang Won Byun, Kyeongseok Jeon, Yun‐Hui Jeon, Uni Park, Hyo Jin Ro, Hyo Ree Park, Yuri Kim, Dong‐Sup Lee, Seok Chung, Young Keun Kim, Nam‐Hyuk Cho
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Advanced Science
Subjects:
cancer immunotherapy
dendritic cells
immunotherapy
iron‐oxide zinc oxide nanoparticles
spheroid
stromal vascular fraction
Online Access:https://doi.org/10.1002/advs.202203842

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