Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence
Acceptance of rotavirus (RV) vaccination may be impacted by several factors including the feasibility of the full schedule administration within the fixed immunization timelines. The human RV vaccine Rotarix (GSK) and the human bovine reassortant vaccine RotaTeq (Merck & Co.) were developed with...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-05-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2020.1816109 |
| _version_ | 1797677266974539776 |
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| author | Domenico Martinelli Francesca Fortunato Federico Marchetti Rosa Prato |
| author_facet | Domenico Martinelli Francesca Fortunato Federico Marchetti Rosa Prato |
| author_sort | Domenico Martinelli |
| collection | DOAJ |
| description | Acceptance of rotavirus (RV) vaccination may be impacted by several factors including the feasibility of the full schedule administration within the fixed immunization timelines. The human RV vaccine Rotarix (GSK) and the human bovine reassortant vaccine RotaTeq (Merck & Co.) were developed with different posologies (2 doses vs 3 doses respectively), which have both scientific and technical implications. A non-systematic literature review revealed that, in the Italian context, topics such as time to achieve RV protection in children, number of preventable cases and administration time window, compatibility/ease of inclusion in the national vaccination calendar, potential overlaps with the peak of natural history of intussusception and adherence to posology could be impacted by the RV vaccine posology. Results suggest that a shorter schedule would allow for greater flexibility of use as well as a greater documented ease of inclusion in the vaccination calendar, thereby reducing potential direct healthcare costs. |
| first_indexed | 2024-03-11T22:41:35Z |
| format | Article |
| id | doaj.art-2fdeeec4c3ef47de83a3250d061b658d |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:41:35Z |
| publishDate | 2021-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-2fdeeec4c3ef47de83a3250d061b658d2023-09-22T08:51:51ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-05-011751546155110.1080/21645515.2020.18161091816109Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherenceDomenico Martinelli0Francesca Fortunato1Federico Marchetti2Rosa Prato3Università di FoggiaUniversità di FoggiaGSKUniversità di FoggiaAcceptance of rotavirus (RV) vaccination may be impacted by several factors including the feasibility of the full schedule administration within the fixed immunization timelines. The human RV vaccine Rotarix (GSK) and the human bovine reassortant vaccine RotaTeq (Merck & Co.) were developed with different posologies (2 doses vs 3 doses respectively), which have both scientific and technical implications. A non-systematic literature review revealed that, in the Italian context, topics such as time to achieve RV protection in children, number of preventable cases and administration time window, compatibility/ease of inclusion in the national vaccination calendar, potential overlaps with the peak of natural history of intussusception and adherence to posology could be impacted by the RV vaccine posology. Results suggest that a shorter schedule would allow for greater flexibility of use as well as a greater documented ease of inclusion in the vaccination calendar, thereby reducing potential direct healthcare costs.http://dx.doi.org/10.1080/21645515.2020.1816109rotavirusvaccineitalyscheduleadministrationcomplianceadherencegastro-enteritischildrenpediatric vaccination |
| spellingShingle | Domenico Martinelli Francesca Fortunato Federico Marchetti Rosa Prato Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence Human Vaccines & Immunotherapeutics rotavirus vaccine italy schedule administration compliance adherence gastro-enteritis children pediatric vaccination |
| title | Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence |
| title_full | Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence |
| title_fullStr | Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence |
| title_full_unstemmed | Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence |
| title_short | Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence |
| title_sort | rotavirus vaccine administration patterns in italy potential impact on vaccine coverage compliance and adherence |
| topic | rotavirus vaccine italy schedule administration compliance adherence gastro-enteritis children pediatric vaccination |
| url | http://dx.doi.org/10.1080/21645515.2020.1816109 |
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