Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together
Sarcopenia is a prevalent condition in patients with Crohn’s disease (CD), representing an independent predictor factor for the development of major postoperative complications. Thus, a proper assessment of the muscle strength, by using different validated tools, should be deemed an important step o...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-04-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/13/4/1378 |
| _version_ | 1797537038264696832 |
|---|---|
| author | Francesco Palmese Rossella Del Toro Giulia Di Marzio Pierluigi Cataleta Maria Giulia Sama Marco Domenicali |
| author_facet | Francesco Palmese Rossella Del Toro Giulia Di Marzio Pierluigi Cataleta Maria Giulia Sama Marco Domenicali |
| author_sort | Francesco Palmese |
| collection | DOAJ |
| description | Sarcopenia is a prevalent condition in patients with Crohn’s disease (CD), representing an independent predictor factor for the development of major postoperative complications. Thus, a proper assessment of the muscle strength, by using different validated tools, should be deemed an important step of the clinical management of these patients. Patients with CD are frequently malnourished, presenting a high prevalence of different macro- and micro-nutrient deficiencies, including that of vitamin D. The available published studies indicate that vitamin D is involved in the regulation of proliferation, differentiation, and regeneration of muscle cells. The relationship between vitamin D deficiency and sarcopenia has been extensively studied in other populations, with interesting evidence in regards to a potential role of vitamin D supplementation as a means to prevent and treat sarcopenia. The aim of this review was to find studies that linked together these pathological conditions. |
| first_indexed | 2024-03-10T12:09:25Z |
| format | Article |
| id | doaj.art-2fdfaf75e95e4aaab7778a627d6e9cce |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T12:09:25Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-2fdfaf75e95e4aaab7778a627d6e9cce2023-11-21T16:16:57ZengMDPI AGNutrients2072-66432021-04-01134137810.3390/nu13041378Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked TogetherFrancesco Palmese0Rossella Del Toro1Giulia Di Marzio2Pierluigi Cataleta3Maria Giulia Sama4Marco Domenicali5Department of Internal Medicine, AUSL della Romagna, S. Maria delle Croci Hospital, 48121 Ravenna, ItalyDepartment of Internal Medicine, AUSL della Romagna, S. Maria delle Croci Hospital, 48121 Ravenna, ItalyDepartment of Experimental and Clinical Medicine, University of Florence, Careggi University Hospital, 50139 Florence, ItalyDepartment of Internal Medicine, AUSL della Romagna, S. Maria delle Croci Hospital, 48121 Ravenna, ItalyDepartment of Internal Medicine, AUSL della Romagna, S. Maria delle Croci Hospital, 48121 Ravenna, ItalyDepartment of Internal Medicine, AUSL della Romagna, S. Maria delle Croci Hospital, 48121 Ravenna, ItalySarcopenia is a prevalent condition in patients with Crohn’s disease (CD), representing an independent predictor factor for the development of major postoperative complications. Thus, a proper assessment of the muscle strength, by using different validated tools, should be deemed an important step of the clinical management of these patients. Patients with CD are frequently malnourished, presenting a high prevalence of different macro- and micro-nutrient deficiencies, including that of vitamin D. The available published studies indicate that vitamin D is involved in the regulation of proliferation, differentiation, and regeneration of muscle cells. The relationship between vitamin D deficiency and sarcopenia has been extensively studied in other populations, with interesting evidence in regards to a potential role of vitamin D supplementation as a means to prevent and treat sarcopenia. The aim of this review was to find studies that linked together these pathological conditions.https://www.mdpi.com/2072-6643/13/4/1378sarcopeniavitamin DCrohn’s diseaseinflammatory bowel diseasenutritional assessmentmalnutrition |
| spellingShingle | Francesco Palmese Rossella Del Toro Giulia Di Marzio Pierluigi Cataleta Maria Giulia Sama Marco Domenicali Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together Nutrients sarcopenia vitamin D Crohn’s disease inflammatory bowel disease nutritional assessment malnutrition |
| title | Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together |
| title_full | Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together |
| title_fullStr | Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together |
| title_full_unstemmed | Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together |
| title_short | Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together |
| title_sort | sarcopenia and vitamin d deficiency in patients with crohn s disease pathological conditions that should be linked together |
| topic | sarcopenia vitamin D Crohn’s disease inflammatory bowel disease nutritional assessment malnutrition |
| url | https://www.mdpi.com/2072-6643/13/4/1378 |
| work_keys_str_mv | AT francescopalmese sarcopeniaandvitaminddeficiencyinpatientswithcrohnsdiseasepathologicalconditionsthatshouldbelinkedtogether AT rosselladeltoro sarcopeniaandvitaminddeficiencyinpatientswithcrohnsdiseasepathologicalconditionsthatshouldbelinkedtogether AT giuliadimarzio sarcopeniaandvitaminddeficiencyinpatientswithcrohnsdiseasepathologicalconditionsthatshouldbelinkedtogether AT pierluigicataleta sarcopeniaandvitaminddeficiencyinpatientswithcrohnsdiseasepathologicalconditionsthatshouldbelinkedtogether AT mariagiuliasama sarcopeniaandvitaminddeficiencyinpatientswithcrohnsdiseasepathologicalconditionsthatshouldbelinkedtogether AT marcodomenicali sarcopeniaandvitaminddeficiencyinpatientswithcrohnsdiseasepathologicalconditionsthatshouldbelinkedtogether |