Phase separation of multiphase droplets in a digital microfluidic device
Abstract This study reports the first comprehensive investigation of separation of the immiscible phases of multiphase droplets in digital microfluidics (DMF) platform. Electrowetting-on-dielectric (EWOD) actuation has been used to mechanically separate the phases. Phase separation performance in te...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-10-01
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| Series: | Micro and Nano Systems Letters |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40486-019-0099-0 |
| _version_ | 1818268216810536960 |
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| author | Mun Mun Nahar Hyejin Moon |
| author_facet | Mun Mun Nahar Hyejin Moon |
| author_sort | Mun Mun Nahar |
| collection | DOAJ |
| description | Abstract This study reports the first comprehensive investigation of separation of the immiscible phases of multiphase droplets in digital microfluidics (DMF) platform. Electrowetting-on-dielectric (EWOD) actuation has been used to mechanically separate the phases. Phase separation performance in terms of percentage residue of one phase into another phase has been quantified. It was conceived that the residue formation can be controlled by controlling the deformation of the phases. The larger capillary number of the neck forming phase is associated with the larger amount of deformation as well as more residue. In this study, we propose two different ways to control the deformation of the phases. In the first method, we applied different EWOD operation voltages on two phases to maintain equal capillary numbers during phase separation. In the second method, while keeping the applied voltages same on both sides, we tested the phase separation performance by varying the actuation schemes. Less than 2% of residue was achieved by both methods, which is almost 90% improvement compared to the phase separation by the conventional droplet splitting technique in EWOD DMF platform, where the residue percentage can go up to 20%. |
| first_indexed | 2024-12-12T20:34:58Z |
| format | Article |
| id | doaj.art-2fe29f018bc0449e98c2e681ce9adcf5 |
| institution | Directory Open Access Journal |
| issn | 2213-9621 |
| language | English |
| last_indexed | 2024-12-12T20:34:58Z |
| publishDate | 2019-10-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Micro and Nano Systems Letters |
| spelling | doaj.art-2fe29f018bc0449e98c2e681ce9adcf52022-12-22T00:12:56ZengSpringerOpenMicro and Nano Systems Letters2213-96212019-10-017111010.1186/s40486-019-0099-0Phase separation of multiphase droplets in a digital microfluidic deviceMun Mun Nahar0Hyejin Moon1Mechanical and Aerospace Engineering Department, University of Texas at ArlingtonMechanical and Aerospace Engineering Department, University of Texas at ArlingtonAbstract This study reports the first comprehensive investigation of separation of the immiscible phases of multiphase droplets in digital microfluidics (DMF) platform. Electrowetting-on-dielectric (EWOD) actuation has been used to mechanically separate the phases. Phase separation performance in terms of percentage residue of one phase into another phase has been quantified. It was conceived that the residue formation can be controlled by controlling the deformation of the phases. The larger capillary number of the neck forming phase is associated with the larger amount of deformation as well as more residue. In this study, we propose two different ways to control the deformation of the phases. In the first method, we applied different EWOD operation voltages on two phases to maintain equal capillary numbers during phase separation. In the second method, while keeping the applied voltages same on both sides, we tested the phase separation performance by varying the actuation schemes. Less than 2% of residue was achieved by both methods, which is almost 90% improvement compared to the phase separation by the conventional droplet splitting technique in EWOD DMF platform, where the residue percentage can go up to 20%.http://link.springer.com/article/10.1186/s40486-019-0099-0Electrowetting-on-dielectricDigital microfluidicsMultiphase dropletCompound dropletPhase separationDroplet splitting |
| spellingShingle | Mun Mun Nahar Hyejin Moon Phase separation of multiphase droplets in a digital microfluidic device Micro and Nano Systems Letters Electrowetting-on-dielectric Digital microfluidics Multiphase droplet Compound droplet Phase separation Droplet splitting |
| title | Phase separation of multiphase droplets in a digital microfluidic device |
| title_full | Phase separation of multiphase droplets in a digital microfluidic device |
| title_fullStr | Phase separation of multiphase droplets in a digital microfluidic device |
| title_full_unstemmed | Phase separation of multiphase droplets in a digital microfluidic device |
| title_short | Phase separation of multiphase droplets in a digital microfluidic device |
| title_sort | phase separation of multiphase droplets in a digital microfluidic device |
| topic | Electrowetting-on-dielectric Digital microfluidics Multiphase droplet Compound droplet Phase separation Droplet splitting |
| url | http://link.springer.com/article/10.1186/s40486-019-0099-0 |
| work_keys_str_mv | AT munmunnahar phaseseparationofmultiphasedropletsinadigitalmicrofluidicdevice AT hyejinmoon phaseseparationofmultiphasedropletsinadigitalmicrofluidicdevice |