Mechanism and Role of Endoplasmic Reticulum Stress in Osteosarcoma

Mechanism and Role of Endoplasmic Reticulum Stress in Osteosarcoma

Osteosarcoma is the most common malignant bone tumor, often occurring in children and adolescents. The etiology of most patients is unclear, and the current conventional treatment methods are chemotherapy, radiotherapy, and surgical resection. However, the sensitivity of osteosarcoma to radiotherapy...

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Bibliographic Details
Main Authors: Peijun Zhu, Ting Li, Qingqing Li, Yawen Gu, Yuan Shu, Kaibo Hu, Leifeng Chen, Xiaogang Peng, Jie Peng, Liang Hao
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
osteosarcoma
endoplasmic reticulum stress
unfolded protein response
autophagy
oxidative stress
therapy
Online Access:https://www.mdpi.com/2218-273X/12/12/1882

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