The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations]
Timely progression of people living with HIV (PLHIV) from the point of infection through the pathway from diagnosis to treatment is important in ensuring effective care and treatment of HIV and preventing HIV-related deaths and onwards transmission of infection. Reliable, population-based estimates...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2017-11-01
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| Series: | Gates Open Research |
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| Online Access: | https://gatesopenresearch.org/articles/1-4/v1 |
| _version_ | 1819005889401585664 |
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| author | Emma Slaymaker Estelle McLean Alison Wringe Clara Calvert Milly Marston Georges Reniers Chodziwadziwa Whiteson Kabudula Amelia Crampin Alison Price Denna Michael Mark Urassa Daniel Kwaro Maquins Sewe Jeffrey W. Eaton Rebecca Rhead Jessica Nakiyingi-Miiro Tom Lutalo Dorean Nabukalu Kobus Herbst Victoria Hosegood Basia Zaba |
| author_facet | Emma Slaymaker Estelle McLean Alison Wringe Clara Calvert Milly Marston Georges Reniers Chodziwadziwa Whiteson Kabudula Amelia Crampin Alison Price Denna Michael Mark Urassa Daniel Kwaro Maquins Sewe Jeffrey W. Eaton Rebecca Rhead Jessica Nakiyingi-Miiro Tom Lutalo Dorean Nabukalu Kobus Herbst Victoria Hosegood Basia Zaba |
| author_sort | Emma Slaymaker |
| collection | DOAJ |
| description | Timely progression of people living with HIV (PLHIV) from the point of infection through the pathway from diagnosis to treatment is important in ensuring effective care and treatment of HIV and preventing HIV-related deaths and onwards transmission of infection. Reliable, population-based estimates of new infections are difficult to obtain for the generalised epidemics in sub-Saharan Africa. Mortality data indicate disease burden and, if disaggregated along the continuum from diagnosis to treatment, can also reflect the coverage and quality of different HIV services. Neither routine statistics nor observational clinical studies can estimate mortality prior to linkage to care nor following disengagement from care. For this, population-based data are required. The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa brings together studies in Kenya, Malawi, South Africa, Tanzania, Uganda, and Zimbabwe. Eight studies have the necessary data to estimate mortality by HIV status, and seven can estimate mortality at different stages of the HIV care continuum. This data note describes a harmonised dataset containing anonymised individual-level information on survival by HIV status for adults aged 15 and above. Among PLHIV, the dataset provides information on survival during different periods: prior to diagnosis of infection; following diagnosis but before linkage to care; in pre-antiretroviral treatment (ART) care; in the first six months after ART initiation; among people continuously on ART for 6+ months; and among people who have ever interrupted ART. |
| first_indexed | 2024-12-20T23:59:58Z |
| format | Article |
| id | doaj.art-2feb575539d04b3aa5a822b4b8d672c0 |
| institution | Directory Open Access Journal |
| issn | 2572-4754 |
| language | English |
| last_indexed | 2024-12-20T23:59:58Z |
| publishDate | 2017-11-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | Gates Open Research |
| spelling | doaj.art-2feb575539d04b3aa5a822b4b8d672c02022-12-21T19:22:37ZengF1000 Research LtdGates Open Research2572-47542017-11-01110.12688/gatesopenres.12753.113813The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations]Emma Slaymaker0Estelle McLean1Alison Wringe2Clara Calvert3Milly Marston4Georges Reniers5Chodziwadziwa Whiteson Kabudula6Amelia Crampin7Alison Price8Denna Michael9Mark Urassa10Daniel Kwaro11Maquins Sewe12Jeffrey W. Eaton13Rebecca Rhead14Jessica Nakiyingi-Miiro15Tom Lutalo16Dorean Nabukalu17Kobus Herbst18Victoria Hosegood19Basia Zaba20Department of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2000, South AfricaDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKNational Institute for Medical Research, Mwanza, TanzaniaNational Institute for Medical Research, Mwanza, TanzaniaKenya Medical Research Institute, Kisumu, KenyaKenya Medical Research Institute, Kisumu, KenyaDepartment of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UKDepartment of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UKMRC/UVRI Uganda Research Unit on AIDS, Entebbe, UgandaRakai Health Sciences Program, Entebbe, UgandaRakai Health Sciences Program, Entebbe, UgandaAfrica Health Research Institute, Durban, 4001, South AfricaAfrica Health Research Institute, Durban, 4001, South AfricaDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UKTimely progression of people living with HIV (PLHIV) from the point of infection through the pathway from diagnosis to treatment is important in ensuring effective care and treatment of HIV and preventing HIV-related deaths and onwards transmission of infection. Reliable, population-based estimates of new infections are difficult to obtain for the generalised epidemics in sub-Saharan Africa. Mortality data indicate disease burden and, if disaggregated along the continuum from diagnosis to treatment, can also reflect the coverage and quality of different HIV services. Neither routine statistics nor observational clinical studies can estimate mortality prior to linkage to care nor following disengagement from care. For this, population-based data are required. The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa brings together studies in Kenya, Malawi, South Africa, Tanzania, Uganda, and Zimbabwe. Eight studies have the necessary data to estimate mortality by HIV status, and seven can estimate mortality at different stages of the HIV care continuum. This data note describes a harmonised dataset containing anonymised individual-level information on survival by HIV status for adults aged 15 and above. Among PLHIV, the dataset provides information on survival during different periods: prior to diagnosis of infection; following diagnosis but before linkage to care; in pre-antiretroviral treatment (ART) care; in the first six months after ART initiation; among people continuously on ART for 6+ months; and among people who have ever interrupted ART.https://gatesopenresearch.org/articles/1-4/v1EpidemiologyHIV Infection & AIDS: Clinical |
| spellingShingle | Emma Slaymaker Estelle McLean Alison Wringe Clara Calvert Milly Marston Georges Reniers Chodziwadziwa Whiteson Kabudula Amelia Crampin Alison Price Denna Michael Mark Urassa Daniel Kwaro Maquins Sewe Jeffrey W. Eaton Rebecca Rhead Jessica Nakiyingi-Miiro Tom Lutalo Dorean Nabukalu Kobus Herbst Victoria Hosegood Basia Zaba The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations] Gates Open Research Epidemiology HIV Infection & AIDS: Clinical |
| title | The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations] |
| title_full | The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations] |
| title_fullStr | The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations] |
| title_full_unstemmed | The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations] |
| title_short | The Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA): Data on mortality, by HIV status and stage on the HIV care continuum, among the general population in seven longitudinal studies between 1989 and 2014 [version 1; referees: 2 approved, 1 approved with reservations] |
| title_sort | network for analysing longitudinal population based hiv aids data on africa alpha data on mortality by hiv status and stage on the hiv care continuum among the general population in seven longitudinal studies between 1989 and 2014 version 1 referees 2 approved 1 approved with reservations |
| topic | Epidemiology HIV Infection & AIDS: Clinical |
| url | https://gatesopenresearch.org/articles/1-4/v1 |
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networkforanalysinglongitudinalpopulationbasedhivaidsdataonafricaalphadataonmortalitybyhivstatusandstageonthehivcarecontinuumamongthegeneralpopulationinsevenlongitudinalstudiesbetween1989and2014version1referees2approved1approvedwithreservations AT victoriahosegood networkforanalysinglongitudinalpopulationbasedhivaidsdataonafricaalphadataonmortalitybyhivstatusandstageonthehivcarecontinuumamongthegeneralpopulationinsevenlongitudinalstudiesbetween1989and2014version1referees2approved1approvedwithreservations AT basiazaba networkforanalysinglongitudinalpopulationbasedhivaidsdataonafricaalphadataonmortalitybyhivstatusandstageonthehivcarecontinuumamongthegeneralpopulationinsevenlongitudinalstudiesbetween1989and2014version1referees2approved1approvedwithreservations |