D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome

D-Chiro-Inositol Treatment Affects Oocyte and Embryo Quality and Improves Glucose Intolerance in Both Aged Mice and Mouse Models of Polycystic Ovarian Syndrome

Polycystic ovarian syndrome (PCOS) is the main cause of female infertility. It is a multifactorial disorder with varying clinical manifestations including metabolic/endocrine abnormalities, hyperandrogenism, and ovarian cysts, among other conditions. D-<i>Chiro</i>-inositol (DCI) is the...

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Bibliographic Details
Main Authors: Eva Pericuesta, Ricardo Laguna-Barraza, Priscila Ramos-Ibeas, Julia L. Gutierrez-Arroyo, Juan A. Navarro, Katia Vera, Carlos Sanjuan, Elena Baixeras, Fernando Rodríguez de Fonseca, Alfonso Gutierrez-Adan
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic ovary syndrome
D-chiro-inositol
oocyte
embryo
fertility
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/21/17/6049

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