Stimulatory, but not anxiogenic, doses of caffeine act centrally to activate interscapular brown adipose tissue thermogenesis in anesthetized male rats
Abstract The role of central orexin in the sympathetic control of interscapular brown adipose tissue (iBAT) thermogenesis has been established in rodents. Stimulatory doses of caffeine activate orexin positive neurons in the lateral hypothalamus, a region of the brain implicated in stimulating BAT t...
Main Authors: | L. Van Schaik, C. Kettle, R. Green, W. Sievers, M. W. Hale, H. R. Irving, D. R. Whelan, J. A. Rathner |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-80505-9 |
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