Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases

The breath gas analysis through gas phase chemical analysis draws attention in terms of non-invasive and real time monitoring. The array-type sensors are one of the diagnostic methods with high sensitivity and selectivity towards the target gases. Herein, we presented a 2 × 4 sensor array with a mic...

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Main Authors: Gwang Su Kim, Yumin Park, Joonchul Shin, Young Geun Song, Chong-Yun Kang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/21/5/1922
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author Gwang Su Kim
Yumin Park
Joonchul Shin
Young Geun Song
Chong-Yun Kang
author_facet Gwang Su Kim
Yumin Park
Joonchul Shin
Young Geun Song
Chong-Yun Kang
author_sort Gwang Su Kim
collection DOAJ
description The breath gas analysis through gas phase chemical analysis draws attention in terms of non-invasive and real time monitoring. The array-type sensors are one of the diagnostic methods with high sensitivity and selectivity towards the target gases. Herein, we presented a 2 × 4 sensor array with a micro-heater and ceramic chip. The device is designed in a small size for portability, including the internal eight-channel sensor array. In<sub>2</sub>O<sub>3</sub> NRs and WO<sub>3</sub> NRs manufactured through the E-beam evaporator’s glancing angle method were used as sensing materials. Pt, Pd, and Au metal catalysts were decorated for each channel to enhance functionality. The sensor array was measured for the exhaled gas biomarkers CH<sub>3</sub>COCH<sub>3</sub>, NO<sub>2</sub>, and H<sub>2</sub>S to confirm the respiratory diagnostic performance. Through this operation, the theoretical detection limit was calculated as 1.48 ppb for CH<sub>3</sub>COCH<sub>3</sub>, 1.9 ppt for NO<sub>2</sub>, and 2.47 ppb for H<sub>2</sub>S. This excellent detection performance indicates that our sensor array detected the CH<sub>3</sub>COCH<sub>3</sub>, NO<sub>2</sub>, and H<sub>2</sub>S as biomarkers, applying to the breath gas analysis. Our results showed the high potential of the gas sensor array as a non-invasive diagnostic tool that enables real-time monitoring.
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spelling doaj.art-2ff66432323b43238a8ef7e98dd6222e2023-11-21T09:48:47ZengMDPI AGSensors1424-82202021-03-01215192210.3390/s21051922Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker GasesGwang Su Kim0Yumin Park1Joonchul Shin2Young Geun Song3Chong-Yun Kang4KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, KoreaKU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, KoreaElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul 02791, KoreaElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul 02791, KoreaKU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, KoreaThe breath gas analysis through gas phase chemical analysis draws attention in terms of non-invasive and real time monitoring. The array-type sensors are one of the diagnostic methods with high sensitivity and selectivity towards the target gases. Herein, we presented a 2 × 4 sensor array with a micro-heater and ceramic chip. The device is designed in a small size for portability, including the internal eight-channel sensor array. In<sub>2</sub>O<sub>3</sub> NRs and WO<sub>3</sub> NRs manufactured through the E-beam evaporator’s glancing angle method were used as sensing materials. Pt, Pd, and Au metal catalysts were decorated for each channel to enhance functionality. The sensor array was measured for the exhaled gas biomarkers CH<sub>3</sub>COCH<sub>3</sub>, NO<sub>2</sub>, and H<sub>2</sub>S to confirm the respiratory diagnostic performance. Through this operation, the theoretical detection limit was calculated as 1.48 ppb for CH<sub>3</sub>COCH<sub>3</sub>, 1.9 ppt for NO<sub>2</sub>, and 2.47 ppb for H<sub>2</sub>S. This excellent detection performance indicates that our sensor array detected the CH<sub>3</sub>COCH<sub>3</sub>, NO<sub>2</sub>, and H<sub>2</sub>S as biomarkers, applying to the breath gas analysis. Our results showed the high potential of the gas sensor array as a non-invasive diagnostic tool that enables real-time monitoring.https://www.mdpi.com/1424-8220/21/5/1922semiconducting gas sensorarraynanostructuremetal oxide
spellingShingle Gwang Su Kim
Yumin Park
Joonchul Shin
Young Geun Song
Chong-Yun Kang
Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases
Sensors
semiconducting gas sensor
array
nanostructure
metal oxide
title Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases
title_full Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases
title_fullStr Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases
title_full_unstemmed Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases
title_short Metal Oxide Nanorods-Based Sensor Array for Selective Detection of Biomarker Gases
title_sort metal oxide nanorods based sensor array for selective detection of biomarker gases
topic semiconducting gas sensor
array
nanostructure
metal oxide
url https://www.mdpi.com/1424-8220/21/5/1922
work_keys_str_mv AT gwangsukim metaloxidenanorodsbasedsensorarrayforselectivedetectionofbiomarkergases
AT yuminpark metaloxidenanorodsbasedsensorarrayforselectivedetectionofbiomarkergases
AT joonchulshin metaloxidenanorodsbasedsensorarrayforselectivedetectionofbiomarkergases
AT younggeunsong metaloxidenanorodsbasedsensorarrayforselectivedetectionofbiomarkergases
AT chongyunkang metaloxidenanorodsbasedsensorarrayforselectivedetectionofbiomarkergases