Effectiveness of miltefosine-pentoxifylline compared to miltefosine in the treatment of cutaneous leishmaniasis in C57Bl/6 mice

Effectiveness of miltefosine-pentoxifylline compared to miltefosine in the treatment of cutaneous leishmaniasis in C57Bl/6 mice

Introduction The treatment of leishmaniasis ischallenging, given the difficulties in drug administration and resistance. Therefore, we chose to test the efficacy of miltefosine combined with pentoxifylline. Methods Twenty-seven isogenic C57Bl/6 mice were infected with Leishmania (Leishmania) amazon...

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Bibliographic Details
Main Authors:	Ana Angélica Amorim Santarem, Gabriel Frizon Greggianin, Rafaela Garcia Debastiani, Jefferson Bruno Pereira Ribeiro, Demerson Andre Polli, Raimunda Nonata Ribeiro Sampaio
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Medicina Tropical (SBMT) 2014-07-01
Series:	Revista da Sociedade Brasileira de Medicina Tropical
Subjects:	Cutaneous leishmaniasis Pentoxifylline Miltefosine
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400517&lng=en&tlng=en

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