Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis

Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis

Cytokines, demyelination and neuroaxonal degeneration in the central nervous system are pivotal elements implicated in the pathogenesis of multiple sclerosis (MS) and its nonclinical model of experimental autoimmune encephalomyelitis (EAE). Phycocyanobilin (PCB), a chromophore of the biliprotein C-P...

Full description

Bibliographic Details
Main Authors: Javier Marín-Prida, Nancy Pavón-Fuentes, Nielsen Lagumersindez-Denis, Hanlet Camacho-Rodríguez, Ana Margarita García-Soca, Rocío de la Caridad Sarduy-Chávez, Érica Leandro Marciano Vieira, Juliana Carvalho-Tavares, Viviana Falcón-Cama, Julio Raúl Fernández-Massó, Ignacio Hernández-González, Gillian Martínez-Donato, Gerardo Guillén-Nieto, Eduardo Pentón-Arias, Mauro Martins Teixeira, Giselle Pentón-Rol
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
interferon-β
proinflammatory cytokines
remyelination
antioxidants
experimental autoimmune encephalomyelitis
multiple sclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036200/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036200/full

Similar Items