Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a

Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a

Objective(s): Chronic kidney disease (CKD), accompanied by renal dysfunction, fibrosis, and apoptosis, is highly prevalent in postmenopausal women. We tested the hypothesis that isoflavone daidzein may ameliorate renal dysfunction and fibrosis through angiotensin II type 1 (AT1R) and angiotensin 1-7...

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Bibliographic Details
Main Authors: Majid Askaripour, Hamid Najafipour, Shadan Saberi, Saleh Yazdani, Saeideh Jafarinejad-Farsangi, Soodeh Rajabi, Elham Jafari, Paul Proost, Sofie Struyf, Fariba Poosti
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
angiotensin receptor
apoptosis
daidzein
micrornas
ovariectomy
renal fibrosis
Online Access:https://ijbms.mums.ac.ir/article_21107_72e87d7722c860bd30e3cc7815231d54.pdf

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