New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system

Introduction: Vitamin C (Vit C) is an organic chemical compound from the group of unsaturated polyhydroxy alcohols. It influences physiological processes such as the facilitation of iron absorption, hormone and carnitine synthesis, and is also involved in epigenetic processes. It is a vitamin, whic...

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Main Authors: Justyna Adamus, Kamila Abram, Patryk Banaś, Jakub Rafał Pierzchała, Katarzyna Bednarz, Natalia Sobańska, Aleksandra Paulina Banasiak, Rafał Teichman, Jakub Kasprowicz, Michał Hyjek
Format: Article
Language:English
Published: Kazimierz Wielki University 2023-02-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/41877
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author Justyna Adamus
Kamila Abram
Patryk Banaś
Jakub Rafał Pierzchała
Katarzyna Bednarz
Natalia Sobańska
Aleksandra Paulina Banasiak
Rafał Teichman
Jakub Kasprowicz
Michał Hyjek
author_facet Justyna Adamus
Kamila Abram
Patryk Banaś
Jakub Rafał Pierzchała
Katarzyna Bednarz
Natalia Sobańska
Aleksandra Paulina Banasiak
Rafał Teichman
Jakub Kasprowicz
Michał Hyjek
author_sort Justyna Adamus
collection DOAJ
description Introduction: Vitamin C (Vit C) is an organic chemical compound from the group of unsaturated polyhydroxy alcohols. It influences physiological processes such as the facilitation of iron absorption, hormone and carnitine synthesis, and is also involved in epigenetic processes. It is a vitamin, which means that it must be provided in food. It is also an antioxidant used as a food additive. In recent times, its pleiotropic use has been proven in the treatment of immune deficiencies, the treatment of skin diseases, bone diseases and may also be used in new cancer treatment regimens.   Aim of the study: To review the current literature on the use of vitamin C in various fields of health and science.    Materials and Methods: We reviewed the literature available in PubMed, using the key words: "vitamin C"; "ascorbid acid"; "cancer treatment"; "vitamin C immune function".   Results: Vitamin C has pleiotropic effects on the human body, both through its effects on cells and tissues and through its antioxidant mechanisms and regulation of gene expression. It has been shown to be a key antioxidant with anti-inflammatory and immune system supportive effects. Its effect of slowing down skin photo-ageing by reducing the amount of metalloproteinases induced by reactive oxygen species has been noted in the literature. Vitamin C has been shown in studies to reduce the risk of osteoporosis due to its osteoclast inhibitory properties. Beneficial effects of high-dose intravenous infusions have also been demonstrated in the treatment of cancer, as well as about reducing organ failure and vascular damage in patients with ARDS and sepsis.   Summary: The versatile action of vitamin C has made it the subject of intense research. However, the reports in the literature to date on its use require further studies on larger groups of people to confirm its effects.
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spelling doaj.art-2ffda26ee7884a0a87f7a819667142572023-02-08T11:44:15ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-02-0113310.12775/JEHS.2023.13.03.031New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune systemJustyna Adamus0Kamila Abram1Patryk Banaś2Jakub Rafał Pierzchała3Katarzyna Bednarz4Natalia Sobańska5Aleksandra Paulina Banasiak6Rafał Teichman7Jakub Kasprowicz8Michał Hyjek9Zespół Szpitali Miejskich w ChorzowieSPZOZ MSWiA w Katowicach im .Sierżanta Grzegorza Załogi w KatowicachSzpital Zakonu Bonifratrów pw. Aniołów Stróżów w KatowicachSamodzielny Publiczny Szpital Kliniczny Nr 4 w LublinieWojewódzki Szpital Specjalistyczny Nr 1 imienia Fryderyka Chopina w RzeszowieWojewódzki Szpital Specjalistyczny Nr 1 imienia Fryderyka Chopina w Rzeszowie1 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ w LublinieWojewódzki Szpital Specjalistyczny Nr 1 imienia Fryderyka Chopina w RzeszowieSamodzielny Publiczny Szpital Kliniczny Nr 4 w LublinieIndependent Public Clinical Hospital No.1 in Lublin Introduction: Vitamin C (Vit C) is an organic chemical compound from the group of unsaturated polyhydroxy alcohols. It influences physiological processes such as the facilitation of iron absorption, hormone and carnitine synthesis, and is also involved in epigenetic processes. It is a vitamin, which means that it must be provided in food. It is also an antioxidant used as a food additive. In recent times, its pleiotropic use has been proven in the treatment of immune deficiencies, the treatment of skin diseases, bone diseases and may also be used in new cancer treatment regimens.   Aim of the study: To review the current literature on the use of vitamin C in various fields of health and science.    Materials and Methods: We reviewed the literature available in PubMed, using the key words: "vitamin C"; "ascorbid acid"; "cancer treatment"; "vitamin C immune function".   Results: Vitamin C has pleiotropic effects on the human body, both through its effects on cells and tissues and through its antioxidant mechanisms and regulation of gene expression. It has been shown to be a key antioxidant with anti-inflammatory and immune system supportive effects. Its effect of slowing down skin photo-ageing by reducing the amount of metalloproteinases induced by reactive oxygen species has been noted in the literature. Vitamin C has been shown in studies to reduce the risk of osteoporosis due to its osteoclast inhibitory properties. Beneficial effects of high-dose intravenous infusions have also been demonstrated in the treatment of cancer, as well as about reducing organ failure and vascular damage in patients with ARDS and sepsis.   Summary: The versatile action of vitamin C has made it the subject of intense research. However, the reports in the literature to date on its use require further studies on larger groups of people to confirm its effects. https://apcz.umk.pl/JEHS/article/view/41877vitamin Cascorbid acidtreatmen cancervitamin C immune function
spellingShingle Justyna Adamus
Kamila Abram
Patryk Banaś
Jakub Rafał Pierzchała
Katarzyna Bednarz
Natalia Sobańska
Aleksandra Paulina Banasiak
Rafał Teichman
Jakub Kasprowicz
Michał Hyjek
New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system
Journal of Education, Health and Sport
vitamin C
ascorbid acid
treatmen cancer
vitamin C immune function
title New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system
title_full New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system
title_fullStr New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system
title_full_unstemmed New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system
title_short New uses for vitamin C, and its versatile, pleiotropic antioxidant action. - Treatment of neoplasms, skin diseases, bone diseases and stimulation of the immune system
title_sort new uses for vitamin c and its versatile pleiotropic antioxidant action treatment of neoplasms skin diseases bone diseases and stimulation of the immune system
topic vitamin C
ascorbid acid
treatmen cancer
vitamin C immune function
url https://apcz.umk.pl/JEHS/article/view/41877
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