Preparation, urease inhibition mechanisms, and anti-Helicobacter pylori activities of hesperetin-7-rhamnoglucoside

Preparation, urease inhibition mechanisms, and anti-Helicobacter pylori activities of hesperetin-7-rhamnoglucoside

This work investigated the effects of the bioflavonoid hesperetin-7-rhamnoglucoside isolated from Citrus uranium fruit peel on Helicobacter pylori (H. pylori). Separation and purity, crystalline state, and urease inhibition assays were carried out. Then, molecular docking and molecular dynamics (MD)...

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Bibliographic Details
Main Authors: Mohamed Sharaf, Muhammad Arif, Hamed I. Hamouda, Sohaib Khan, Mohnad Abdalla, Samah Shabana, Hussein. E. Rozan, Tehsin Ullah Khan, Zhe Chi, Chenguang Liu
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Microbial Sciences
Subjects:
Helicobacter pylori
Hesperidin
Antimicrobial
Anti-urease
Molecular docking
Molecular dynamics simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517421000833

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