Two Centers Affiliated to Shiraz University of Medical Sciences
Background & aim: Colonoscopy is the main method of colon examination. Acceptable bowel preparation plays an effective role in examining the bowel. Diagnosis and treatment of colon polyps or non-bulging lesions such as vascular malformations and serrated polyps depend on the degree of intestinal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | fas |
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Yasuj University Of Medical Sciences
2023-04-01
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| Series: | Armaghane Danesh Bimonthly Journal |
| Subjects: | |
| Online Access: | http://armaghanj.yums.ac.ir/article-1-3458-en.pdf |
| _version_ | 1827798129502584832 |
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| author | M Alizadeh Nayini A Molvi M Ghorbani F Banaei |
| author_facet | M Alizadeh Nayini A Molvi M Ghorbani F Banaei |
| author_sort | M Alizadeh Nayini |
| collection | DOAJ |
| description | Background & aim: Colonoscopy is the main method of colon examination. Acceptable bowel preparation plays an effective role in examining the bowel. Diagnosis and treatment of colon polyps or non-bulging lesions such as vascular malformations and serrated polyps depend on the degree of intestinal cleanliness at the time of assessment. On the other hand, insufficient preparation makes the evaluation more difficult, the evaluation is incomplete, increases the time of colonoscopy and the need to repeat the procedure, and this increases the cost. Therefore, the purpose of the present study was to determine and prepare the large intestine for colonoscopy with pidrolox produced in Iran with and without Senagraf syrup in two centers affiliated to Shiraz University of Medical Sciences.
Methods: In the present prospective, double-blind descriptive study conducted in 2016 on 273 patients in need of non-emergency colonoscopy referred to Shahid Motahari and Shahid Faqihi clinics of Shiraz, Iran, 227 patients were randomly selected into two drug (111) and control groups. (116) were categorized and studied. The effect of adding Senagraf to pidrolox manufactured in Iran with pidrolox along with placebo on the level of intestinal readiness (based on Ottawa scoring) in eligible patients (20-78 years old) who were willing to enter the study was investigated and compared. Collected data were analyzed using Mann-Whitney, Kruskal-Wallis and Chi-square statistical tests.
Results: The average score of intestinal cleanliness in whole and as well by different parts, in the drug group, was lower than the control group, which confirms better preparation (p=0.001). Compared to older people, younger people had cleaner intestines (p=0.001). The level of bowel preparation in female patients was also better than male patients (p=0.001). The travel time from the rectum to the cecum and the return time from the cecum to the rectum were significantly less than the control group (p=0.001). No significant side effects were observed in both groups.
Conclusion: Adding senna to Iranian polyethylene glycol (PEG) before colonoscopy increased bowel preparation and reduces colonoscopy time, without causing additional side effects. |
| first_indexed | 2024-03-11T19:31:33Z |
| format | Article |
| id | doaj.art-3000440fbc72477e8674e981144cb05a |
| institution | Directory Open Access Journal |
| issn | 1728-6506 1728-6514 |
| language | fas |
| last_indexed | 2024-03-11T19:31:33Z |
| publishDate | 2023-04-01 |
| publisher | Yasuj University Of Medical Sciences |
| record_format | Article |
| series | Armaghane Danesh Bimonthly Journal |
| spelling | doaj.art-3000440fbc72477e8674e981144cb05a2023-10-06T13:16:11ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65061728-65142023-04-01283371385Two Centers Affiliated to Shiraz University of Medical SciencesM Alizadeh Nayini0A Molvi1M Ghorbani2F Banaei3 Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Department of Epidemiology and Biostatistics, Torbat Heydarieh University of Medical Sciences, Torbat Heydarieh, Iran Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Background & aim: Colonoscopy is the main method of colon examination. Acceptable bowel preparation plays an effective role in examining the bowel. Diagnosis and treatment of colon polyps or non-bulging lesions such as vascular malformations and serrated polyps depend on the degree of intestinal cleanliness at the time of assessment. On the other hand, insufficient preparation makes the evaluation more difficult, the evaluation is incomplete, increases the time of colonoscopy and the need to repeat the procedure, and this increases the cost. Therefore, the purpose of the present study was to determine and prepare the large intestine for colonoscopy with pidrolox produced in Iran with and without Senagraf syrup in two centers affiliated to Shiraz University of Medical Sciences. Methods: In the present prospective, double-blind descriptive study conducted in 2016 on 273 patients in need of non-emergency colonoscopy referred to Shahid Motahari and Shahid Faqihi clinics of Shiraz, Iran, 227 patients were randomly selected into two drug (111) and control groups. (116) were categorized and studied. The effect of adding Senagraf to pidrolox manufactured in Iran with pidrolox along with placebo on the level of intestinal readiness (based on Ottawa scoring) in eligible patients (20-78 years old) who were willing to enter the study was investigated and compared. Collected data were analyzed using Mann-Whitney, Kruskal-Wallis and Chi-square statistical tests. Results: The average score of intestinal cleanliness in whole and as well by different parts, in the drug group, was lower than the control group, which confirms better preparation (p=0.001). Compared to older people, younger people had cleaner intestines (p=0.001). The level of bowel preparation in female patients was also better than male patients (p=0.001). The travel time from the rectum to the cecum and the return time from the cecum to the rectum were significantly less than the control group (p=0.001). No significant side effects were observed in both groups. Conclusion: Adding senna to Iranian polyethylene glycol (PEG) before colonoscopy increased bowel preparation and reduces colonoscopy time, without causing additional side effects.http://armaghanj.yums.ac.ir/article-1-3458-en.pdfcolonoscopybowel preparationottawapolyethylene glycolsenagraph |
| spellingShingle | M Alizadeh Nayini A Molvi M Ghorbani F Banaei Two Centers Affiliated to Shiraz University of Medical Sciences Armaghane Danesh Bimonthly Journal colonoscopy bowel preparation ottawa polyethylene glycol senagraph |
| title | Two Centers Affiliated to Shiraz University of Medical Sciences |
| title_full | Two Centers Affiliated to Shiraz University of Medical Sciences |
| title_fullStr | Two Centers Affiliated to Shiraz University of Medical Sciences |
| title_full_unstemmed | Two Centers Affiliated to Shiraz University of Medical Sciences |
| title_short | Two Centers Affiliated to Shiraz University of Medical Sciences |
| title_sort | two centers affiliated to shiraz university of medical sciences |
| topic | colonoscopy bowel preparation ottawa polyethylene glycol senagraph |
| url | http://armaghanj.yums.ac.ir/article-1-3458-en.pdf |
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