Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis
New pharmacologic advances in the treatment of diabetes include SGLT-2 inhibitors, which have been demonstrated in randomized-controlled clinical trials to reduce overall and cardiac-specific mortality and slow progression of chronic kidney disease. Euglycemic diabetic ketoacidosis is a rare but lif...
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Format: | Article |
Language: | English |
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Elsevier
2021-12-01
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Series: | Journal of Vascular Surgery Cases and Innovative Techniques |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2468428721001805 |
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author | Clara M. Gomez-Sanchez, MD Bian X. Wu, MD Jeffrey E. Gotts, MD Robert W. Chang, MD |
author_facet | Clara M. Gomez-Sanchez, MD Bian X. Wu, MD Jeffrey E. Gotts, MD Robert W. Chang, MD |
author_sort | Clara M. Gomez-Sanchez, MD |
collection | DOAJ |
description | New pharmacologic advances in the treatment of diabetes include SGLT-2 inhibitors, which have been demonstrated in randomized-controlled clinical trials to reduce overall and cardiac-specific mortality and slow progression of chronic kidney disease. Euglycemic diabetic ketoacidosis is a rare but life-threatening complication associated with the use of SGLT-2 inhibitors. Here we describe a case of severe euglycemic diabetic ketoacidosis after lower extremity bypass in a patient taking an SGLT-2 inhibitor. Awareness of this potential complication is essential as these novel agents are increasingly used in patients with cardiovascular disease. |
first_indexed | 2024-12-24T01:30:52Z |
format | Article |
id | doaj.art-3006de9df1f84acda593c0de6bbb7600 |
institution | Directory Open Access Journal |
issn | 2468-4287 |
language | English |
last_indexed | 2024-12-24T01:30:52Z |
publishDate | 2021-12-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Vascular Surgery Cases and Innovative Techniques |
spelling | doaj.art-3006de9df1f84acda593c0de6bbb76002022-12-21T17:22:21ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872021-12-0174778780Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosisClara M. Gomez-Sanchez, MD0Bian X. Wu, MD1Jeffrey E. Gotts, MD2Robert W. Chang, MD3Division of Vascular and Endovascular Surgery, Department of Surgery, University of California San Francisco, San Francisco, Calif; Correspondence: Clara M. Gomez-Sanchez, MD, University of California San Francisco, San Francisco, 400 Parnassus Ave, Ste A-581, San Francisco, CA 94143Department of Vascular Surgery, Kaiser Permanente Northern California, Oakland, CalifDepartment of Critical Care Medicine, Kaiser Permanente Northern California, Oakland, CalifDepartment of Vascular Surgery, Kaiser Permanente Northern California, Oakland, CalifNew pharmacologic advances in the treatment of diabetes include SGLT-2 inhibitors, which have been demonstrated in randomized-controlled clinical trials to reduce overall and cardiac-specific mortality and slow progression of chronic kidney disease. Euglycemic diabetic ketoacidosis is a rare but life-threatening complication associated with the use of SGLT-2 inhibitors. Here we describe a case of severe euglycemic diabetic ketoacidosis after lower extremity bypass in a patient taking an SGLT-2 inhibitor. Awareness of this potential complication is essential as these novel agents are increasingly used in patients with cardiovascular disease.http://www.sciencedirect.com/science/article/pii/S2468428721001805Peripheral artery diseaseDiabetic acidosisSGLT-2 inhibitorsPostoperative complication |
spellingShingle | Clara M. Gomez-Sanchez, MD Bian X. Wu, MD Jeffrey E. Gotts, MD Robert W. Chang, MD Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis Journal of Vascular Surgery Cases and Innovative Techniques Peripheral artery disease Diabetic acidosis SGLT-2 inhibitors Postoperative complication |
title | Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis |
title_full | Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis |
title_fullStr | Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis |
title_full_unstemmed | Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis |
title_short | Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis |
title_sort | euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis |
topic | Peripheral artery disease Diabetic acidosis SGLT-2 inhibitors Postoperative complication |
url | http://www.sciencedirect.com/science/article/pii/S2468428721001805 |
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