Oral microbial extracellular DNA initiates periodontitis through gingival degradation by fibroblast-derived cathepsin K in mice
A highly sensitive imaging probe shows that oral microbial extracellular DNA triggers early activity of Ctsk in gingival fibroblasts, initiating periodontitis in mice.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03896-7 |
| Summary: | A highly sensitive imaging probe shows that oral microbial extracellular DNA triggers early activity of Ctsk in gingival fibroblasts, initiating periodontitis in mice. |
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| ISSN: | 2399-3642 |