Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI)
Traumatic brain injury (TBI) occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently impacts an object or when an object pierces the skull and enters brain tissue. Secondary injuries after traumatic brain injury (TBI) can lead to impairments on cer...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/21/5/1586 |
| _version_ | 1797395355059355648 |
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| author | María Roldán Panayiotis A. Kyriacou |
| author_facet | María Roldán Panayiotis A. Kyriacou |
| author_sort | María Roldán |
| collection | DOAJ |
| description | Traumatic brain injury (TBI) occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently impacts an object or when an object pierces the skull and enters brain tissue. Secondary injuries after traumatic brain injury (TBI) can lead to impairments on cerebral oxygenation and autoregulation. Considering that secondary brain injuries often take place within the first hours after the trauma, noninvasive monitoring might be helpful in providing early information on the brain’s condition. Near-infrared spectroscopy (NIRS) is an emerging noninvasive monitoring modality based on chromophore absorption of infrared light with the capability of monitoring perfusion of the brain. This review investigates the main applications of NIRS in TBI monitoring and presents a thorough revision of those applications on oxygenation and autoregulation monitoring. Databases such as PubMed, EMBASE, Web of Science, Scopus, and Cochrane library were utilized in identifying 72 publications spanning between 1977 and 2020 which were directly relevant to this review. The majority of the evidence found used NIRS for diagnosis applications, especially in oxygenation and autoregulation monitoring (59%). It was not surprising that nearly all the patients were male adults with severe trauma who were monitored mostly with continue wave NIRS or spatially resolved spectroscopy NIRS and an invasive monitoring device. In general, a high proportion of the assessed papers have concluded that NIRS could be a potential noninvasive technique for assessing TBI, despite the various methodological and technological limitations of NIRS. |
| first_indexed | 2024-03-09T00:34:21Z |
| format | Article |
| id | doaj.art-300fbb8e48f54f9a97041847bb3c0b4b |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-09T00:34:21Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-300fbb8e48f54f9a97041847bb3c0b4b2023-12-11T18:17:09ZengMDPI AGSensors1424-82202021-02-01215158610.3390/s21051586Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI)María Roldán0Panayiotis A. Kyriacou1Research Centre for Biomedical Engineering, School of Mathematics, Computer Sciences and Engineering, University of London, London EC1V 0HB, UKResearch Centre for Biomedical Engineering, School of Mathematics, Computer Sciences and Engineering, University of London, London EC1V 0HB, UKTraumatic brain injury (TBI) occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently impacts an object or when an object pierces the skull and enters brain tissue. Secondary injuries after traumatic brain injury (TBI) can lead to impairments on cerebral oxygenation and autoregulation. Considering that secondary brain injuries often take place within the first hours after the trauma, noninvasive monitoring might be helpful in providing early information on the brain’s condition. Near-infrared spectroscopy (NIRS) is an emerging noninvasive monitoring modality based on chromophore absorption of infrared light with the capability of monitoring perfusion of the brain. This review investigates the main applications of NIRS in TBI monitoring and presents a thorough revision of those applications on oxygenation and autoregulation monitoring. Databases such as PubMed, EMBASE, Web of Science, Scopus, and Cochrane library were utilized in identifying 72 publications spanning between 1977 and 2020 which were directly relevant to this review. The majority of the evidence found used NIRS for diagnosis applications, especially in oxygenation and autoregulation monitoring (59%). It was not surprising that nearly all the patients were male adults with severe trauma who were monitored mostly with continue wave NIRS or spatially resolved spectroscopy NIRS and an invasive monitoring device. In general, a high proportion of the assessed papers have concluded that NIRS could be a potential noninvasive technique for assessing TBI, despite the various methodological and technological limitations of NIRS.https://www.mdpi.com/1424-8220/21/5/1586near infrared spectroscopytraumatic brain injurycerebral oxygenationcerebral autoregulation |
| spellingShingle | María Roldán Panayiotis A. Kyriacou Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI) Sensors near infrared spectroscopy traumatic brain injury cerebral oxygenation cerebral autoregulation |
| title | Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI) |
| title_full | Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI) |
| title_fullStr | Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI) |
| title_full_unstemmed | Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI) |
| title_short | Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI) |
| title_sort | near infrared spectroscopy nirs in traumatic brain injury tbi |
| topic | near infrared spectroscopy traumatic brain injury cerebral oxygenation cerebral autoregulation |
| url | https://www.mdpi.com/1424-8220/21/5/1586 |
| work_keys_str_mv | AT mariaroldan nearinfraredspectroscopynirsintraumaticbraininjurytbi AT panayiotisakyriacou nearinfraredspectroscopynirsintraumaticbraininjurytbi |