Alternative Splicing of Human Telomerase Reverse Transcriptase (hTERT) and Its Implications in Physiological and Pathological Processes

Alternative Splicing of Human Telomerase Reverse Transcriptase (hTERT) and Its Implications in Physiological and Pathological Processes

Alternative splicing (AS) of human telomerase catalytic subunit (hTERT, human telomerase reverse transcriptase) pre-mRNA strongly regulates telomerase activity. Several proteins can regulate AS in a cell type-specific manner and determine the functions of cells. In addition to being involved in telo...

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Bibliographic Details
Main Authors: Anna A. Plyasova, Dmitry D. Zhdanov
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
alternative splicing
telomerase
splice variants
human telomerase reverse transcriptase (hTERT)
telomeres
lymphocytes
Online Access:https://www.mdpi.com/2227-9059/9/5/526

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