Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration

Myocardial infarction (MI) permanently damages cardiac tissue. Tissue engineering exhibits tremendous potential as a strategy for developing engineered tissue to repair congenital abnormalities in the heart and/or cardiovascular tissue. Electroconductive hydrogels (EHs) are prepared from synthetic o...

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Main Authors: Xu Yan, Huan Sun, Ping Yang
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2022/6042137
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author Xu Yan
Huan Sun
Ping Yang
author_facet Xu Yan
Huan Sun
Ping Yang
author_sort Xu Yan
collection DOAJ
description Myocardial infarction (MI) permanently damages cardiac tissue. Tissue engineering exhibits tremendous potential as a strategy for developing engineered tissue to repair congenital abnormalities in the heart and/or cardiovascular tissue. Electroconductive hydrogels (EHs) are prepared from synthetic or natural biodegradable polymers and conductive components that could partially restore the myocardial/ventricular electromechanical coupling and synchronized heartbeats. Also, EHs are ideal materials for the preparation of cell culture and induction carriers, engineered scaffolds, and patches, as well as cell and gene delivery carriers, all of which aid in tissue formation. Except for a brief introduction to the classification and synthesis of EHs, this review discussed the recent progress and challenges of EHs applied in cardiac repair and regeneration to provide a reference for the further application of EHs in treating cardiovascular diseases. Figure abstract: the EHs categorization and the potential application of heart repair and regeneration in this review.
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spelling doaj.art-3010a00c263446a2baf9ed4c681730cb2022-12-22T04:04:40ZengHindawi LimitedAdvances in Materials Science and Engineering1687-84422022-01-01202210.1155/2022/6042137Recent Advances on Electroconductive Hydrogels Used in Heart Repair and RegenerationXu Yan0Huan Sun1Ping Yang2Cardiology DepartmentCardiology DepartmentCardiology DepartmentMyocardial infarction (MI) permanently damages cardiac tissue. Tissue engineering exhibits tremendous potential as a strategy for developing engineered tissue to repair congenital abnormalities in the heart and/or cardiovascular tissue. Electroconductive hydrogels (EHs) are prepared from synthetic or natural biodegradable polymers and conductive components that could partially restore the myocardial/ventricular electromechanical coupling and synchronized heartbeats. Also, EHs are ideal materials for the preparation of cell culture and induction carriers, engineered scaffolds, and patches, as well as cell and gene delivery carriers, all of which aid in tissue formation. Except for a brief introduction to the classification and synthesis of EHs, this review discussed the recent progress and challenges of EHs applied in cardiac repair and regeneration to provide a reference for the further application of EHs in treating cardiovascular diseases. Figure abstract: the EHs categorization and the potential application of heart repair and regeneration in this review.http://dx.doi.org/10.1155/2022/6042137
spellingShingle Xu Yan
Huan Sun
Ping Yang
Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration
Advances in Materials Science and Engineering
title Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration
title_full Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration
title_fullStr Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration
title_full_unstemmed Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration
title_short Recent Advances on Electroconductive Hydrogels Used in Heart Repair and Regeneration
title_sort recent advances on electroconductive hydrogels used in heart repair and regeneration
url http://dx.doi.org/10.1155/2022/6042137
work_keys_str_mv AT xuyan recentadvancesonelectroconductivehydrogelsusedinheartrepairandregeneration
AT huansun recentadvancesonelectroconductivehydrogelsusedinheartrepairandregeneration
AT pingyang recentadvancesonelectroconductivehydrogelsusedinheartrepairandregeneration