Sialic acid and platelet count regulation: Implications in immune thrombocytopenia

Sialic acid and platelet count regulation: Implications in immune thrombocytopenia

Abstract Platelets are blood components that survive in circulation for 7 to 10 days in humans. Thus, platelet production by bone marrow (BM) megakaryocytes (MKs), and their removal from the blood circulation is precisely orchestrated to maintain an average platelet count. Abnormalities in both proc...

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Bibliographic Details
Main Authors: Melissa M. Lee‐Sundlov, Leonardo Rivadeneyra, Hervé Falet, Karin M. Hoffmeister
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
glycans
immune thrombocytopenia
megakaryocytes
platelets
sialic acid
Online Access:https://doi.org/10.1002/rth2.12691

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