Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges
Cardio-cerebrovascular diseases are the leading cause of death worldwide and there is currently no optimal treatment plan. Chinese herbal medicine injection (CHI) is obtained by combining traditional Chinese medicine (TCM) theory and modern production technology. It retains some characteristics of T...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1038906/full |
| _version_ | 1797895395554099200 |
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| author | Jiang Huajuan Jiang Huajuan Huang Xulong Huang Xulong Xian Bin Xian Bin Wang Yue Wang Yue Zhou Yongfeng Zhou Yongfeng Ren Chaoxiang Ren Chaoxiang Pei Jin Pei Jin |
| author_facet | Jiang Huajuan Jiang Huajuan Huang Xulong Huang Xulong Xian Bin Xian Bin Wang Yue Wang Yue Zhou Yongfeng Zhou Yongfeng Ren Chaoxiang Ren Chaoxiang Pei Jin Pei Jin |
| author_sort | Jiang Huajuan |
| collection | DOAJ |
| description | Cardio-cerebrovascular diseases are the leading cause of death worldwide and there is currently no optimal treatment plan. Chinese herbal medicine injection (CHI) is obtained by combining traditional Chinese medicine (TCM) theory and modern production technology. It retains some characteristics of TCM while adding injection characteristics. CHI has played an important role in the treatment of critical diseases, especially cardio-cerebrovascular diseases, and has shown unique therapeutic advantages. TCMs that promote blood circulation and remove blood stasis, such as Salvia miltiorrhiza, Carthami flos, Panax notoginseng, and Chuanxiong rhizoma, account for a large proportion of CHIs of cardio-cerebrovascular disease. CHI is used to treat cardio-cerebrovascular diseases and has potential pharmacological activities such as anti-platelet aggregation, anti-inflammatory, anti-fibrosis, and anti-apoptosis. However, CHIs have changed the traditional method of administering TCMs, and the drugs directly enter the bloodstream, which may produce new pharmacological effects or adverse reactions. This article summarizes the clinical application, pharmacological effects, and mechanism of action of different varieties of CHIs commonly used in the treatment of cardio-cerebrovascular diseases, analyzes the causes of adverse reactions, and proposes suggestions for rational drug use and pharmaceutical care methods to provide a reference for the rational application of CHIs for cardio-cerebrovascular diseases. |
| first_indexed | 2024-04-10T07:26:11Z |
| format | Article |
| id | doaj.art-301298cd463d430ca062c852a5a0b479 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-10T07:26:11Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-301298cd463d430ca062c852a5a0b4792023-02-24T06:06:06ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-02-011410.3389/fphar.2023.10389061038906Chinese herbal injection for cardio-cerebrovascular disease: Overview and challengesJiang Huajuan0Jiang Huajuan1Huang Xulong2Huang Xulong3Xian Bin4Xian Bin5Wang Yue6Wang Yue7Zhou Yongfeng8Zhou Yongfeng9Ren Chaoxiang10Ren Chaoxiang11Pei Jin12Pei Jin13State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, ChinaPharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaCardio-cerebrovascular diseases are the leading cause of death worldwide and there is currently no optimal treatment plan. Chinese herbal medicine injection (CHI) is obtained by combining traditional Chinese medicine (TCM) theory and modern production technology. It retains some characteristics of TCM while adding injection characteristics. CHI has played an important role in the treatment of critical diseases, especially cardio-cerebrovascular diseases, and has shown unique therapeutic advantages. TCMs that promote blood circulation and remove blood stasis, such as Salvia miltiorrhiza, Carthami flos, Panax notoginseng, and Chuanxiong rhizoma, account for a large proportion of CHIs of cardio-cerebrovascular disease. CHI is used to treat cardio-cerebrovascular diseases and has potential pharmacological activities such as anti-platelet aggregation, anti-inflammatory, anti-fibrosis, and anti-apoptosis. However, CHIs have changed the traditional method of administering TCMs, and the drugs directly enter the bloodstream, which may produce new pharmacological effects or adverse reactions. This article summarizes the clinical application, pharmacological effects, and mechanism of action of different varieties of CHIs commonly used in the treatment of cardio-cerebrovascular diseases, analyzes the causes of adverse reactions, and proposes suggestions for rational drug use and pharmaceutical care methods to provide a reference for the rational application of CHIs for cardio-cerebrovascular diseases.https://www.frontiersin.org/articles/10.3389/fphar.2023.1038906/fullChinese herbal injectioncardio-cerebrovascular diseasesclinical applicationpharmacological effectstraditional Chinese medicine |
| spellingShingle | Jiang Huajuan Jiang Huajuan Huang Xulong Huang Xulong Xian Bin Xian Bin Wang Yue Wang Yue Zhou Yongfeng Zhou Yongfeng Ren Chaoxiang Ren Chaoxiang Pei Jin Pei Jin Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges Frontiers in Pharmacology Chinese herbal injection cardio-cerebrovascular diseases clinical application pharmacological effects traditional Chinese medicine |
| title | Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges |
| title_full | Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges |
| title_fullStr | Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges |
| title_full_unstemmed | Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges |
| title_short | Chinese herbal injection for cardio-cerebrovascular disease: Overview and challenges |
| title_sort | chinese herbal injection for cardio cerebrovascular disease overview and challenges |
| topic | Chinese herbal injection cardio-cerebrovascular diseases clinical application pharmacological effects traditional Chinese medicine |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1038906/full |
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