Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation

Many diseases are linked to dysregulation of the striatum. Striatal function depends on neuronal compartmentation into striosomes and matrix. Striatal projection neurons are GABAergic medium spiny neurons (MSNs), subtyped by selective expression of receptors, neuropeptides, and other gene families....

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Main Authors: Maria-Daniela Cirnaru, Sicheng Song, Kizito-Tshitoko Tshilenge, Chuhyon Corwin, Justyna Mleczko, Carlos Galicia Aguirre, Houda Benlhabib, Jaroslav Bendl, Pasha Apontes, John Fullard, Jordi Creus-Muncunill, Azadeh Reyahi, Ali M Nik, Peter Carlsson, Panos Roussos, Sean D Mooney, Lisa M Ellerby, Michelle E Ehrlich
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
Striosome
Olig2
striatum
Nr4a1
Foxf2
transcription factors
Online Access:https://elifesciences.org/articles/65979

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