Prediction accuracy of regulatory elements from sequence varies by functional sequencing technique

Prediction accuracy of regulatory elements from sequence varies by functional sequencing technique

IntroductionVarious sequencing based approaches are used to identify and characterize the activities of cis-regulatory elements in a genome-wide fashion. Some of these techniques rely on indirect markers such as histone modifications (ChIP-seq with histone antibodies) or chromatin accessibility (ATA...

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Bibliographic Details
Main Authors: Ronald J. Nowling, Kimani Njoya, John G. Peters, Michelle M. Riehle
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
enhancers
functional sequencing
machine learning
sequence models
DNase-seq
STARR-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1182567/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1182567/full

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