Role of Renin-Angiotensin System Components in Atherosclerosis: Focus on Ang-II, ACE2, and Ang-1–7

Role of Renin-Angiotensin System Components in Atherosclerosis: Focus on Ang-II, ACE2, and Ang-1–7

Atherosclerosis is the leading cause of vascular disease worldwide and contributes significantly to deaths from cardiovascular complications. There is a remarkably close relationship between atherosclerotic plaque formation and the activation of renin-angiotensin system (RAS). However, depending on...

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Bibliographic Details
Main Authors: Gabriela M. Silva, Maria S. França-Falcão, Natália Tabosa M. Calzerra, Mickael S. Luz, Danilo Duarte A. Gadelha, Camille M. Balarini, Thyago M. Queiroz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Physiology
Subjects:
angiotensin converting enzyme type 2
angiotensin II
angiotensin 1–7
atherosclerosis
endothelial dysfunction
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.01067/full

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