Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes
Extracellular vesicles (Evs) are small spherical vesicles capable of transporting molecules (such as proteins, nucleic acids and lipids) from one cell to another. They have been implicated in processes such as cell-to-cell communication, pathogenicity, biofilm formation and metabolism. In parallel,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/12/4/703 |
| _version_ | 1797606692858363904 |
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| author | Tania Henriquez Chiara Falciani |
| author_facet | Tania Henriquez Chiara Falciani |
| author_sort | Tania Henriquez |
| collection | DOAJ |
| description | Extracellular vesicles (Evs) are small spherical vesicles capable of transporting molecules (such as proteins, nucleic acids and lipids) from one cell to another. They have been implicated in processes such as cell-to-cell communication, pathogenicity, biofilm formation and metabolism. In parallel, Evs have been proposed as interesting biotechnological tools. In recent years, antibiotic resistance has become a major problem for human health worldwide. A pathogen singled out as among the most lethal antibiotic-resistant organisms is <i>Pseudomonas aeruginosa</i>, an important Gram-negative bacterium that has been extensively studied for the production and characterization of Evs. Here, we describe the advances made in the last decade regarding understanding of the role of Evs in the pathogenicity of <i>Pseudomonas.</i> We also examine the potential of Evs for the development of new treatment strategies. |
| first_indexed | 2024-03-11T05:18:40Z |
| format | Article |
| id | doaj.art-301d5b6f58a1448bac10d65febe93fb6 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T05:18:40Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-301d5b6f58a1448bac10d65febe93fb62023-11-17T18:02:47ZengMDPI AGAntibiotics2079-63822023-04-0112470310.3390/antibiotics12040703Extracellular Vesicles of <i>Pseudomonas</i>: Friends and FoesTania Henriquez0Chiara Falciani1Department of Medical Biotechnologies, University of Siena, 53100 Siena, ItalyDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, ItalyExtracellular vesicles (Evs) are small spherical vesicles capable of transporting molecules (such as proteins, nucleic acids and lipids) from one cell to another. They have been implicated in processes such as cell-to-cell communication, pathogenicity, biofilm formation and metabolism. In parallel, Evs have been proposed as interesting biotechnological tools. In recent years, antibiotic resistance has become a major problem for human health worldwide. A pathogen singled out as among the most lethal antibiotic-resistant organisms is <i>Pseudomonas aeruginosa</i>, an important Gram-negative bacterium that has been extensively studied for the production and characterization of Evs. Here, we describe the advances made in the last decade regarding understanding of the role of Evs in the pathogenicity of <i>Pseudomonas.</i> We also examine the potential of Evs for the development of new treatment strategies.https://www.mdpi.com/2079-6382/12/4/703extracellular vesiclesouter membrane vesicles<i>Pseudomonas aeruginosa</i>antibiotic resistancevaccine development |
| spellingShingle | Tania Henriquez Chiara Falciani Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes Antibiotics extracellular vesicles outer membrane vesicles <i>Pseudomonas aeruginosa</i> antibiotic resistance vaccine development |
| title | Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes |
| title_full | Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes |
| title_fullStr | Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes |
| title_full_unstemmed | Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes |
| title_short | Extracellular Vesicles of <i>Pseudomonas</i>: Friends and Foes |
| title_sort | extracellular vesicles of i pseudomonas i friends and foes |
| topic | extracellular vesicles outer membrane vesicles <i>Pseudomonas aeruginosa</i> antibiotic resistance vaccine development |
| url | https://www.mdpi.com/2079-6382/12/4/703 |
| work_keys_str_mv | AT taniahenriquez extracellularvesiclesofipseudomonasifriendsandfoes AT chiarafalciani extracellularvesiclesofipseudomonasifriendsandfoes |