Anaphylaxis caused by taking pantoprazole: case series
Introduction: Pantoprazole is one of the most widely used proton pump inhibitors, but anaphylaxis occurs rarely during its use. The purpose of reporting these two cases is to show that pantoprazole is not a drug without problems; it can also cause anaphylactic reactions. Cases description: A 42-year...
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2023-08-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/4017 |
| _version_ | 1797692518082543616 |
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| author | Skender Telaku Arber Veliu Qendrim Zenelaj Mimoza Telaku Hajrullah Fejza Fitim Alidema |
| author_facet | Skender Telaku Arber Veliu Qendrim Zenelaj Mimoza Telaku Hajrullah Fejza Fitim Alidema |
| author_sort | Skender Telaku |
| collection | DOAJ |
| description | Introduction: Pantoprazole is one of the most widely used proton pump inhibitors, but anaphylaxis occurs rarely during its use. The purpose of reporting these two cases is to show that pantoprazole is not a drug without problems; it can also cause anaphylactic reactions.
Cases description: A 42-year-old woman presented to the emergency department due to dyspeptic complaints. Immediately at the end of the infusion of pantoprazole, there started to be numbness of the tongue, itching all over the body, and difficulty in breathing. Half an hour after taking a pantoprazole 40 mg capsule, a 58-year-old woman started to experience redness of the face, thickening of the tongue, itching, bloating, and dizziness. Arterial pressure was 80/60 mmHg, pulse 150/minute, while saturation had dropped to 88%. In both cases, fluids, adrenaline, antihistamines, methylprednisolone, and calcium were immediately started. After the improvement of their general conditions, both patients were discharged home.
Discussion: The first case relates to anaphylaxis after the intravenous administration of pantoprazole, and the second case relates to the appearance of anaphylaxis after its oral administration.
Conclusion: Health workers need to be informed about the possibility of anaphylaxis in patients taking both oral and parenteral pantoprazole. |
| first_indexed | 2024-03-12T02:28:45Z |
| format | Article |
| id | doaj.art-301da8afe6af4264bf189867d7a8a55e |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-03-12T02:28:45Z |
| publishDate | 2023-08-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-301da8afe6af4264bf189867d7a8a55e2023-09-05T09:56:45ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-08-0110.12890/2023_0040173552Anaphylaxis caused by taking pantoprazole: case seriesSkender Telaku0Arber Veliu1Qendrim Zenelaj2Mimoza Telaku3Hajrullah Fejza4Fitim Alidema5University for Business and Technology, Prishtina, KosovoUniversity and Clinical Center of Kosova, Gastroenterology Department, KosovoUniversity and Clinical Center of Kosova, Gastroenterology Department, KosovaMedical Faculty, Tirana, AlbaniaUniversity for Business and Technology, Prishtina, KosovoUniversity for Business and Technology, Prishtina, KosovaIntroduction: Pantoprazole is one of the most widely used proton pump inhibitors, but anaphylaxis occurs rarely during its use. The purpose of reporting these two cases is to show that pantoprazole is not a drug without problems; it can also cause anaphylactic reactions. Cases description: A 42-year-old woman presented to the emergency department due to dyspeptic complaints. Immediately at the end of the infusion of pantoprazole, there started to be numbness of the tongue, itching all over the body, and difficulty in breathing. Half an hour after taking a pantoprazole 40 mg capsule, a 58-year-old woman started to experience redness of the face, thickening of the tongue, itching, bloating, and dizziness. Arterial pressure was 80/60 mmHg, pulse 150/minute, while saturation had dropped to 88%. In both cases, fluids, adrenaline, antihistamines, methylprednisolone, and calcium were immediately started. After the improvement of their general conditions, both patients were discharged home. Discussion: The first case relates to anaphylaxis after the intravenous administration of pantoprazole, and the second case relates to the appearance of anaphylaxis after its oral administration. Conclusion: Health workers need to be informed about the possibility of anaphylaxis in patients taking both oral and parenteral pantoprazole.https://www.ejcrim.com/index.php/EJCRIM/article/view/4017anaphylactic reactionpantoprazoleproton pump inhibitors |
| spellingShingle | Skender Telaku Arber Veliu Qendrim Zenelaj Mimoza Telaku Hajrullah Fejza Fitim Alidema Anaphylaxis caused by taking pantoprazole: case series European Journal of Case Reports in Internal Medicine anaphylactic reaction pantoprazole proton pump inhibitors |
| title | Anaphylaxis caused by taking pantoprazole: case series |
| title_full | Anaphylaxis caused by taking pantoprazole: case series |
| title_fullStr | Anaphylaxis caused by taking pantoprazole: case series |
| title_full_unstemmed | Anaphylaxis caused by taking pantoprazole: case series |
| title_short | Anaphylaxis caused by taking pantoprazole: case series |
| title_sort | anaphylaxis caused by taking pantoprazole case series |
| topic | anaphylactic reaction pantoprazole proton pump inhibitors |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/4017 |
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