Combined endocrine approaches vs endocrine therapy alone as first line treatment in elderly patients with hormone receptor-positive, HER2 negative, advanced breast cancer: to prescribe for the patient or the physician? A meta-analysis of phase II and III randomized clinical trials

Combined endocrine approaches vs endocrine therapy alone as first line treatment in elderly patients with hormone receptor-positive, HER2 negative, advanced breast cancer: to prescribe for the patient or the physician? A meta-analysis of phase II and III randomized clinical trials

Abstract Background Elderly patients are underrepresented in clinical study where combined endocrine strategies were compared to endocrine therapy (ET) in hormone receptors positive, HER2 negative, metastatic breast cancer. The role of the new endocrine approaches in elderly women is still unclear....

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Bibliographic Details
Main Authors: Claudia Omarini, Federico Piacentini, Isabella Sperduti, Monica Barbolini, Chrystel Isca, Angela Toss, Laura Cortesi, Elena Barbieri, Massimo Dominici, Luca Moscetti
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Metastatic breast cancer
Endocrine therapy
CD4/6 inhibitors
Palbociclib
Ribociclib
Abemaciclib
Online Access:http://link.springer.com/article/10.1186/s12885-020-06933-y

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