Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis
Abstract Among forensic patients with schizophrenia spectrum disorders, the association between symptomatology and violence is still not entirely clear in literature, especially because symptoms shift both during the acute phase of the illness and after. The aims were to investigate the level of sym...
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | Annals of General Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12991-022-00413-2 |
| _version_ | 1828418571965825024 |
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| author | Chiara Buizza Cosmo Strozza Giulio Sbravati Giovanni de Girolamo Clarissa Ferrari Laura Iozzino Ambra Macis Harry G. Kennedy Valentina Candini |
| author_facet | Chiara Buizza Cosmo Strozza Giulio Sbravati Giovanni de Girolamo Clarissa Ferrari Laura Iozzino Ambra Macis Harry G. Kennedy Valentina Candini |
| author_sort | Chiara Buizza |
| collection | DOAJ |
| description | Abstract Among forensic patients with schizophrenia spectrum disorders, the association between symptomatology and violence is still not entirely clear in literature, especially because symptoms shift both during the acute phase of the illness and after. The aims were to investigate the level of symptomatology in forensic patients and to evaluate if there are differences in the level of symptoms between forensic and non-forensic patients. According to PRISMA guidelines, a systematic search was performed in PubMed, Web of Science, and ProQuest, using the following key words: “forensic” AND “Positive and Negative Syndrome Scale” OR “PANSS”. A total of 27 studies were included in the systematic review, while only 23 studies in the meta-analysis. The overall sample included a total of 1702 participants, most commonly male and inpatients in forensic settings. We found that studies with an entirely male sample had significantly lower Positive PANSS ratings than studies with mixed samples. Although both forensic and non-forensic patients were affected by mild psychopathological symptoms, forensic patients presented higher ratings in all four PANSS scales. This meta-analysis shows that forensic patients reported a mild level of symptomatology, as assessed with the PANSS, and therefore might be considered as patients in partial remission. Among patients with schizophrenia, the association between symptoms and violence is very complex: many factors might be considered as key mediators and thus should be taken into account to explain this association. Further studies are needed. Trial registration all materials and data can be found on the OSF framework: https://osf.io/5ceja (date of registration: 8 September 2021) |
| first_indexed | 2024-12-10T14:38:54Z |
| format | Article |
| id | doaj.art-302574513ef34f4c84588ad1b2b8b751 |
| institution | Directory Open Access Journal |
| issn | 1744-859X |
| language | English |
| last_indexed | 2024-12-10T14:38:54Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of General Psychiatry |
| spelling | doaj.art-302574513ef34f4c84588ad1b2b8b7512022-12-22T01:44:44ZengBMCAnnals of General Psychiatry1744-859X2022-09-0121111710.1186/s12991-022-00413-2Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysisChiara Buizza0Cosmo Strozza1Giulio Sbravati2Giovanni de Girolamo3Clarissa Ferrari4Laura Iozzino5Ambra Macis6Harry G. Kennedy7Valentina Candini8Psychiatric Epidemiology and Evaluation Unit, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliInterdisciplinary Centre On Population Dynamics, University of Southern DenmarkPsychiatric Epidemiology and Evaluation Unit, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliPsychiatric Epidemiology and Evaluation Unit, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliService of Statistics, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliPsychiatric Epidemiology and Evaluation Unit, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliService of Statistics, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliThe National Forensic Mental Health Service, Central Mental HospitalPsychiatric Epidemiology and Evaluation Unit, IRCCS Istituto Centro San Giovanni Di Dio FatebenefratelliAbstract Among forensic patients with schizophrenia spectrum disorders, the association between symptomatology and violence is still not entirely clear in literature, especially because symptoms shift both during the acute phase of the illness and after. The aims were to investigate the level of symptomatology in forensic patients and to evaluate if there are differences in the level of symptoms between forensic and non-forensic patients. According to PRISMA guidelines, a systematic search was performed in PubMed, Web of Science, and ProQuest, using the following key words: “forensic” AND “Positive and Negative Syndrome Scale” OR “PANSS”. A total of 27 studies were included in the systematic review, while only 23 studies in the meta-analysis. The overall sample included a total of 1702 participants, most commonly male and inpatients in forensic settings. We found that studies with an entirely male sample had significantly lower Positive PANSS ratings than studies with mixed samples. Although both forensic and non-forensic patients were affected by mild psychopathological symptoms, forensic patients presented higher ratings in all four PANSS scales. This meta-analysis shows that forensic patients reported a mild level of symptomatology, as assessed with the PANSS, and therefore might be considered as patients in partial remission. Among patients with schizophrenia, the association between symptoms and violence is very complex: many factors might be considered as key mediators and thus should be taken into account to explain this association. Further studies are needed. Trial registration all materials and data can be found on the OSF framework: https://osf.io/5ceja (date of registration: 8 September 2021)https://doi.org/10.1186/s12991-022-00413-2Forensic patientSchizophrenia spectrum disordersSymptomatologyPANSSPsychotic symptoms |
| spellingShingle | Chiara Buizza Cosmo Strozza Giulio Sbravati Giovanni de Girolamo Clarissa Ferrari Laura Iozzino Ambra Macis Harry G. Kennedy Valentina Candini Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis Annals of General Psychiatry Forensic patient Schizophrenia spectrum disorders Symptomatology PANSS Psychotic symptoms |
| title | Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis |
| title_full | Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis |
| title_fullStr | Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis |
| title_full_unstemmed | Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis |
| title_short | Positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders: a systematic review and meta-analysis |
| title_sort | positive and negative syndrome scale in forensic patients with schizophrenia spectrum disorders a systematic review and meta analysis |
| topic | Forensic patient Schizophrenia spectrum disorders Symptomatology PANSS Psychotic symptoms |
| url | https://doi.org/10.1186/s12991-022-00413-2 |
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