Quality by Design Approach for the Development of Liposome Carrying Ghrelin for Intranasal Administration

Quality by Design Approach for the Development of Liposome Carrying Ghrelin for Intranasal Administration

The therapeutic use of peptides has increasingly recognized in the development of new therapies. However, the susceptible enzymatic cleavage is a barrier that needs to overcome. Nose-to-brain delivery associated with liposomes can protect peptides against biodegradation and improve the accessibility...

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Bibliographic Details
Main Authors: Cecília de Barros, Norberto Aranha, Patrícia Severino, Eliana B. Souto, Aleksandra Zielińska, André Lopes, Alessandra Rios, Fernando Batain, Kessi Crescencio, Marco Chaud, Thais Alves
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
ghrelin
intranasal rout
liposomes
quality by design (QbD)
cachexia
undernourishment
Online Access:https://www.mdpi.com/1999-4923/13/5/686

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