Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer’s Disease

Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer’s Disease

The brains of Alzheimer’s disease (AD) patients contain numerous amyloid plaques that are diagnostic of the disease. The plaques are primarily composed of the amyloidogenic peptides proteins Aβ40 and Aβ42, which are derived by the processing of the amyloid pre-cursor protein (APP) by two proteases c...

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Bibliographic Details
Main Authors:	Terrone L. Rosenberry, Huan-Xiang Zhou, Scott M. Stagg, Anant K. Paravastu
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Molecules
Subjects:	Alzheimer’s disease Aβ42 oligomer solid-state 2D NMR membranes
Online Access:	https://www.mdpi.com/1420-3049/27/24/8804

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