Novel secretion modification region (SMR) peptide exhibits anti-metastatic properties in human breast cancer cells

Abstract Breast cancer is the second leading cause of cancer-related mortality in women worldwide, with nearly 90% attributed to metastatic progression. Exosomes containing epithelial–mesenchymal transition (EMT) ‘programs’ transmit pro-metastatic phenotypes. Our group discovered and developed a nov...

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Bibliographic Details
Main Authors: Ming-Bo Huang, Dara Brena, Jennifer Y. Wu, William W. Roth, Samuel Owusu, Vincent C. Bond
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17534-z