Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis

Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis

ObjectiveCentral glucagon-like peptide-1 (GLP-1) is a target in treating obesity due to its effect on suppressing appetite, but the possible downstream key genes that GLP-1 regulated have not been studied in depth. This study intends to screen out the downstream feeding regulation genes of central G...

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Bibliographic Details
Main Authors: Yuwei Shao, Jun Tian, Yanan Yang, Yan Hu, Ye Zhu, Qing Shu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neuroscience
Subjects:
glucagon-like peptide-1 (GLP-1)
appetite
obesity
bioinformatics
chemical genetics
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.931161/full

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