Wearable patches for transdermal drug delivery

Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic first-pass metabolism, providing good drug bioavailability and patient compliance. One emerging type of TDDs is the wearable patch worn on the skin surface to deliver medication through the skin. They can general...

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Bibliographic Details
Main Authors: Jiahui He, Yuyue Zhang, Xinge Yu, Chenjie Xu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523001545
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author Jiahui He
Yuyue Zhang
Xinge Yu
Chenjie Xu
author_facet Jiahui He
Yuyue Zhang
Xinge Yu
Chenjie Xu
author_sort Jiahui He
collection DOAJ
description Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic first-pass metabolism, providing good drug bioavailability and patient compliance. One emerging type of TDDs is the wearable patch worn on the skin surface to deliver medication through the skin. They can generally be grouped into passive and active types, depending on the properties of materials, design principles and integrated devices. This review describes the latest advancement in the development of wearable patches, focusing on the integration of stimulus-responsive materials and electronics. This development is deemed to provide a dosage, temporal, and spatial control of therapeutics delivery.
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spelling doaj.art-302c9d77eb4446aa8f0a09f00f0b545c2023-06-30T04:22:01ZengElsevierActa Pharmaceutica Sinica B2211-38352023-06-0113622982309Wearable patches for transdermal drug deliveryJiahui He0Yuyue Zhang1Xinge Yu2Chenjie Xu3Department of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, ChinaDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, ChinaDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, China; Hong Kong Centre for Cerebro-Cardiovascular Health Engineering, Hong Kong 999077, ChinaDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, China; Corresponding author.Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic first-pass metabolism, providing good drug bioavailability and patient compliance. One emerging type of TDDs is the wearable patch worn on the skin surface to deliver medication through the skin. They can generally be grouped into passive and active types, depending on the properties of materials, design principles and integrated devices. This review describes the latest advancement in the development of wearable patches, focusing on the integration of stimulus-responsive materials and electronics. This development is deemed to provide a dosage, temporal, and spatial control of therapeutics delivery.http://www.sciencedirect.com/science/article/pii/S2211383523001545Wearable patchTransdermal deliveryMicroneedlesDrug deliveryBiomaterials
spellingShingle Jiahui He
Yuyue Zhang
Xinge Yu
Chenjie Xu
Wearable patches for transdermal drug delivery
Acta Pharmaceutica Sinica B
Wearable patch
Transdermal delivery
Microneedles
Drug delivery
Biomaterials
title Wearable patches for transdermal drug delivery
title_full Wearable patches for transdermal drug delivery
title_fullStr Wearable patches for transdermal drug delivery
title_full_unstemmed Wearable patches for transdermal drug delivery
title_short Wearable patches for transdermal drug delivery
title_sort wearable patches for transdermal drug delivery
topic Wearable patch
Transdermal delivery
Microneedles
Drug delivery
Biomaterials
url http://www.sciencedirect.com/science/article/pii/S2211383523001545
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AT yuyuezhang wearablepatchesfortransdermaldrugdelivery
AT xingeyu wearablepatchesfortransdermaldrugdelivery
AT chenjiexu wearablepatchesfortransdermaldrugdelivery