Wearable patches for transdermal drug delivery
Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic first-pass metabolism, providing good drug bioavailability and patient compliance. One emerging type of TDDs is the wearable patch worn on the skin surface to deliver medication through the skin. They can general...
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Format: | Article |
Language: | English |
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Elsevier
2023-06-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383523001545 |
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author | Jiahui He Yuyue Zhang Xinge Yu Chenjie Xu |
author_facet | Jiahui He Yuyue Zhang Xinge Yu Chenjie Xu |
author_sort | Jiahui He |
collection | DOAJ |
description | Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic first-pass metabolism, providing good drug bioavailability and patient compliance. One emerging type of TDDs is the wearable patch worn on the skin surface to deliver medication through the skin. They can generally be grouped into passive and active types, depending on the properties of materials, design principles and integrated devices. This review describes the latest advancement in the development of wearable patches, focusing on the integration of stimulus-responsive materials and electronics. This development is deemed to provide a dosage, temporal, and spatial control of therapeutics delivery. |
first_indexed | 2024-03-13T02:24:51Z |
format | Article |
id | doaj.art-302c9d77eb4446aa8f0a09f00f0b545c |
institution | Directory Open Access Journal |
issn | 2211-3835 |
language | English |
last_indexed | 2024-03-13T02:24:51Z |
publishDate | 2023-06-01 |
publisher | Elsevier |
record_format | Article |
series | Acta Pharmaceutica Sinica B |
spelling | doaj.art-302c9d77eb4446aa8f0a09f00f0b545c2023-06-30T04:22:01ZengElsevierActa Pharmaceutica Sinica B2211-38352023-06-0113622982309Wearable patches for transdermal drug deliveryJiahui He0Yuyue Zhang1Xinge Yu2Chenjie Xu3Department of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, ChinaDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, ChinaDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, China; Hong Kong Centre for Cerebro-Cardiovascular Health Engineering, Hong Kong 999077, ChinaDepartment of Biomedical Engineering, City University of Hong Kong, Hong Kong 999077, China; Corresponding author.Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic first-pass metabolism, providing good drug bioavailability and patient compliance. One emerging type of TDDs is the wearable patch worn on the skin surface to deliver medication through the skin. They can generally be grouped into passive and active types, depending on the properties of materials, design principles and integrated devices. This review describes the latest advancement in the development of wearable patches, focusing on the integration of stimulus-responsive materials and electronics. This development is deemed to provide a dosage, temporal, and spatial control of therapeutics delivery.http://www.sciencedirect.com/science/article/pii/S2211383523001545Wearable patchTransdermal deliveryMicroneedlesDrug deliveryBiomaterials |
spellingShingle | Jiahui He Yuyue Zhang Xinge Yu Chenjie Xu Wearable patches for transdermal drug delivery Acta Pharmaceutica Sinica B Wearable patch Transdermal delivery Microneedles Drug delivery Biomaterials |
title | Wearable patches for transdermal drug delivery |
title_full | Wearable patches for transdermal drug delivery |
title_fullStr | Wearable patches for transdermal drug delivery |
title_full_unstemmed | Wearable patches for transdermal drug delivery |
title_short | Wearable patches for transdermal drug delivery |
title_sort | wearable patches for transdermal drug delivery |
topic | Wearable patch Transdermal delivery Microneedles Drug delivery Biomaterials |
url | http://www.sciencedirect.com/science/article/pii/S2211383523001545 |
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