Isolated anti-Ro52 identifies a severe subset of Sjögren’s syndrome patients

Isolated anti-Ro52 identifies a severe subset of Sjögren’s syndrome patients

IntroductionSerum autoantibodies targeting the SSA/Ro proteins are a key component of the classification criteria for the diagnosis of Sjögren’s syndrome (SS). Most patients' serum reacts with both Ro60 and Ro52 proteins. Here we compare the molecular and clinical characteristics of patients di...

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Bibliographic Details
Main Authors: Adrian Y. S. Lee, Trishni Putty, Ming-Wei Lin, Sanjay Swaminathan, Dan Suan, Tim Chataway, Rogier M. Thurlings, Tom P. Gordon, Jing Jing Wang, Joanne H. Reed
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
anti-Ro52/TRIM21
autoantibodies
cryoglobulinaemia
rheumatoid factor, Ro/La
Sjögren’s syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1115548/full

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