Exposure assessment and risk-based limit levels evaluation of ochratoxin A in Astragali Radix in China

Exposure assessment and risk-based limit levels evaluation of ochratoxin A in Astragali Radix in China

Ochratoxin A (OTA) is a mycotoxin found in a variety of foods and herbal medicines, and several governmental bodies around the world have set maximum allowable levels of OTA in different foods and herbal medicines. This study aims to evaluate the health risk of OTA in Astragali Radix (AR) in China,...

Full description

Bibliographic Details
Main Authors:	Yin Zhu, Shaomin Wang, Xiaohui Xu, Lingling Wang, Heng Zhou, Xuanyu Ying, Qing Hu, Xinglong Wang, Shen Ji, Qiang Cai
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	Astragali Radix Ochratoxin A Exposure assessment Health risk Limit level Traditional Chinese medicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651322003578

Similar Items

Evaluation of the Pharmaceutical Properties and Value of Astragali Radix
by: Amy G. W. Gong, et al.
Published: (2018-05-01)

Neuroprotective effect of Astragali Radix on cerebral infarction based on proteomics
by: Ying Li, et al.
Published: (2023-06-01)

Effect of Astragali radix extract on pharmacokinetic behavior of dapagliflozin in healthy and type 2 diabetic rats
by: Wandi Du, et al.
Published: (2023-10-01)

Cysteine-rich peptide fingerprinting as a general method for herbal analysis to differentiate Radix Astragali and Radix Hedysarum
by: Huang, Jiayi, et al.
Published: (2020)

Residue of Chlormequat and Regulatory Effects on the Specialized Metabolites of Astragali Radix
by: Honghan Qin, et al.
Published: (2023-09-01)

Acute and repeated toxicological study of Myelophil, an ethanol extract of a mixture of Astragali Radix and Salviae Miltiorrhizae Radix, in beagle dogs
by: Jin-Yong Joung, et al.
Published: (2019-07-01)

The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells
by: Juan Liu, et al.
Published: (2019-12-01)

Potential Quality Evaluation Method for Radix Astragali Based on Sweetness Indicators
by: Ke Li, et al.
Published: (2015-02-01)

Identification and Determination of Flavonoids in Astragali Radix by High Performance Liquid Chromatography Coupled with DAD and ESI-MS Detection
by: Yu-Ling Wang, et al.
Published: (2011-03-01)

Quantitative Evaluation of Twelve Major Components of Sulfur-Fumigated Astragali Radix with Different Durations by UPLC-MS
by: Xiaoyan Xing, et al.
Published: (2018-10-01)

Effects of Astragali Radix on T lymphocyte subsets expression in peripheral blood of Hashimoto′s thyroiditis patients with normal thyroid function
by: LI Ziyun, et al.
Published: (2024-01-01)

Five Active Components Compatibility of Astragali Radix and Angelicae Sinensis Radix Protect Hematopoietic Function Against Cyclophosphamide-Induced Injury in Mice and t-BHP–Induced Injury in HSCs
by: Wei Zhang, et al.
Published: (2019-08-01)

Quality Markers for Astragali Radix and Its Products Based on Process Analysis
by: Yuntao Dai, et al.
Published: (2020-12-01)

The Effect of Herb-acupunctures of Bojoongiggi-tang (Buzhongyiqi-tang), Ginseng Radix, and Astragali Radix on Immune Responses in Rats
by: Kim, Jung-Hun, et al.
Published: (2000-12-01)

Radix Astragali and Radix Angelicae Sinensis in the Treatment of Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-analysis
by: Yufeng Zhang, et al.
Published: (2020-04-01)

Exploring the potential mechanism of radix astragali against ischemic stroke based on network pharmacology and molecular docking
by: Yang Zhen, et al.
Published: (2022-05-01)

Quality Control of Radix Astragali (The Root of Astragalus membranaceus var. mongholicus) Along Its Value Chains
by: Yaqiong Bi, et al.
Published: (2020-12-01)

Predicting the grades of Astragali radix using mass spectrometry-based metabolomics and machine learning
by: Xinyue Yu, et al.
Published: (2021-10-01)

Comparative analysis of chemical profiles of Radix Astragali between ultrafine granular powder and sliced traditional material
by: Liang Cao, et al.
Published: (2022-01-01)

RETRACTED: Astragali Radix Isoflavones Synergistically Alleviate Cerebral Ischemia and Reperfusion Injury Via Activating Estrogen Receptor-PI3K-Akt Signaling Pathway
by: Yong Gu, et al.
Published: (2021-02-01)

Protective effects of Pharmacopuncture Solutions made by Carthmi Flos, Cnidii Rhizoma and Astragali Radix on C6 glioma cells
by: Hyung Woo Kim, et al.
Published: (2009-06-01)

16S rRNA and Metagenomics Combined with UPLC-Q/TOF-MS Metabolomics Analysis Reveals the Potential Mechanism of Radix Astragali Against Hyperuricemia in Mice
by: Deng S, et al.
Published: (2023-05-01)

The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation
by: Ke-Gang Linghu, et al.
Published: (2022-09-01)

Genetic diversity of the Chinese medicinal plant Astragali Radix based on transcriptome-derived SSR markers
by: Ming Jiang, et al.
Published: (2023-03-01)

Study on the biotransformation and activities of three isoflavone glycosides from Radix Astragali by human feces in vitro
by: Xin Liu, et al.
Published: (2023-08-01)

The Efficacy and Safety of Myelophil, an Ethanol Extract Mixture of Astragali Radix and Salviae Radix, for Chronic Fatigue Syndrome: A Randomized Clinical Trial
by: Jin-Yong Joung, et al.
Published: (2019-09-01)

Combination of Radix Astragali and Safflower Promotes Angiogenesis in Rats with Ischemic Stroke via Silencing PTGS2
by: Shouchao Xu, et al.
Published: (2023-01-01)

Metabolomics combined with network pharmacology exploration reveals the modulatory properties of Astragali Radix extract in the treatment of liver fibrosis
by: Dan Wang, et al.
Published: (2019-08-01)

An evaluation of Astragali Radix with different growth patterns and years, based on a new multidimensional comparison method
by: Yapeng Wang, et al.
Published: (2024-02-01)

Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of <i>Astragali Radix</i>
by: Xiangna Chang, et al.
Published: (2022-02-01)

Exploring the In Vivo Existence Forms (23 Original Constituents and 147 Metabolites) of Astragali Radix Total Flavonoids and Their Distributions in Rats Using HPLC-DAD-ESI-IT-TOF-MS<sup>n</sup>
by: Li-Jia Liu, et al.
Published: (2020-11-01)

Effects of Physical Properties and Processing Methods on Astragaloside IV and Flavonoids Content in <i>Astragali radix</i>
by: Mei-Yin Chien, et al.
Published: (2022-01-01)

Network Pharmacology–Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury
by: Yuan Peng, et al.
Published: (2022-07-01)

The Extracts and Major Compounds Derived from Astragali Radix Alter Mitochondrial Bioenergetics in Cultured Cardiomyocytes: Comparison of Various Polar Solvents and Compounds
by: Yun Huang, et al.
Published: (2018-05-01)

Isolating, Identifying, and Analyzing the Biological Characteristics of Pathogens Causing Postharvest Disease in Fresh <i>Radix Astragali</i>
by: Yuan Zhang, et al.
Published: (2023-09-01)

Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS
by: Liangliang Liu, et al.
Published: (2016-11-01)

Mechanism exploration and prognosis study of Astragali Radix-Spreading hedyotis herb for the treatment of lung adenocarcinoma based on bioinformatics approaches and molecular dynamics simulation
by: Junfeng Guo, et al.
Published: (2023-03-01)

Induction of Angiogenesis in Zebrafish Embryos and Proliferation of Endothelial Cells by an Active Fraction Isolated from the Root of Astragalus membranaceus using Bioassay-guided Fractionation
by: Patrick Kwok-Kin Lai, et al.
Published: (2014-10-01)

Study of the Mechanism of Astragali Radix in Treating Type 2 Diabetes Mellitus and Its Renal Protection Based on Enzyme Activity, Network Pharmacology, and Experimental Verification
by: Chunnan Li, et al.
Published: (2023-12-01)

Development and Validation of a Near-Infrared Spectroscopy Method for Multicomponent Quantification during the Second Alcohol Precipitation Process of <i>Astragali radix</i>
by: Wenlong Li, et al.
Published: (2022-10-01)