Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort
Background The prevalence of obstructive sleep apnoea (OSA) is growing as the population is ageing. However, data on the clinical characteristics of elderly patients with OSA and their adherence to positive airway pressure (PAP) treatment are scarce. Methods Data from 23 418 30–79-year-old OSA patie...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2023-05-01
|
| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/9/3/00506-2022.full |
| _version_ | 1797689332101808128 |
|---|---|
| author | Aino Lammintausta Ulla Anttalainen Özen K. Basoglu Maria R. Bonsignore Haralampos Gouveris Ludger Grote Jan Hedner Ondrej Ludka Stefan Mihaicuta Athanasia Pataka Georgia Trakada Mafalda van Zeller Tarja Saaresranta |
| author_facet | Aino Lammintausta Ulla Anttalainen Özen K. Basoglu Maria R. Bonsignore Haralampos Gouveris Ludger Grote Jan Hedner Ondrej Ludka Stefan Mihaicuta Athanasia Pataka Georgia Trakada Mafalda van Zeller Tarja Saaresranta |
| author_sort | Aino Lammintausta |
| collection | DOAJ |
| description | Background
The prevalence of obstructive sleep apnoea (OSA) is growing as the population is ageing. However, data on the clinical characteristics of elderly patients with OSA and their adherence to positive airway pressure (PAP) treatment are scarce.
Methods
Data from 23 418 30–79-year-old OSA patients prospectively collected into the ESADA database during 2007–2019 were analysed. Information on PAP use (h·day−1) in association with a first follow-up visit was available for 6547 patients. The data was analysed according to 10-year age groups.
Results
The oldest age group was less obese, less sleepy and had a lower apnoea–hypopnoea index (AHI) compared with middle-aged patients. The insomnia phenotype of OSA was more prevalent in the oldest age group than in the middle-aged group (36%, 95% CI 34–38 versus 26%, 95% CI 24–27, p<0.001). The 70–79-year-old group adhered to PAP therapy equally well as the younger age groups with a mean PAP use of 5.59 h·day−1 (95% CI 5.44–5.75). PAP adherence did not differ between clinical phenotypes based on subjective daytime sleepiness and sleep complaints suggestive of insomnia in the oldest age group. A higher score on the Clinical Global Impression Severity (CGI-S) scale predicted poorer PAP adherence.
Conclusion
The elderly patient group was less obese, less sleepy, had more insomnia symptoms and less severe OSA, but were rated to be more ill compared with the middle-aged patients. Elderly patients with OSA adhered to PAP therapy equally well as middle-aged patients. Low global functioning (measured by CGI-S) in the elderly patient predicted poorer PAP adherence. |
| first_indexed | 2024-03-12T01:44:10Z |
| format | Article |
| id | doaj.art-30359cbfae724ae0b9d17f68fd095f9d |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-03-12T01:44:10Z |
| publishDate | 2023-05-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-30359cbfae724ae0b9d17f68fd095f9d2023-09-09T13:53:53ZengEuropean Respiratory SocietyERJ Open Research2312-05412023-05-019310.1183/23120541.00506-202200506-2022Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohortAino Lammintausta0Ulla Anttalainen1Özen K. Basoglu2Maria R. Bonsignore3Haralampos Gouveris4Ludger Grote5Jan Hedner6Ondrej Ludka7Stefan Mihaicuta8Athanasia Pataka9Georgia Trakada10Mafalda van Zeller11Tarja Saaresranta12 Division of Medicine, Department of Pulmonary Diseases and Sleep and Breathing Centre, Turku University Hospital, Turku, Finland Division of Medicine, Department of Pulmonary Diseases and Sleep and Breathing Centre, Turku University Hospital, Turku, Finland Department of Chest Diseases, Ege University, Izmir, Turkey Respiratory Medicine, PROMISE Department, University of Palermo and IRIB-CNR, Palermo, Italy Sleep Medicine Center and Department of Otolaryngology, University Medical Center, Mainz, Germany Department of Sleep Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden Department of Sleep Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden Department of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic Department of Pulmonology, CardioPrevent Foundation, University of Medicine and Pharmacy Victor Babes, Timisoara, Romania Respiratory Failure Unit, G. Papanikolaou Hospital, Aristotle University, Thessaloniki, Greece Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece Division of Medicine, Department of Pulmonary Diseases and Sleep and Breathing Centre, Turku University Hospital, Turku, Finland Background The prevalence of obstructive sleep apnoea (OSA) is growing as the population is ageing. However, data on the clinical characteristics of elderly patients with OSA and their adherence to positive airway pressure (PAP) treatment are scarce. Methods Data from 23 418 30–79-year-old OSA patients prospectively collected into the ESADA database during 2007–2019 were analysed. Information on PAP use (h·day−1) in association with a first follow-up visit was available for 6547 patients. The data was analysed according to 10-year age groups. Results The oldest age group was less obese, less sleepy and had a lower apnoea–hypopnoea index (AHI) compared with middle-aged patients. The insomnia phenotype of OSA was more prevalent in the oldest age group than in the middle-aged group (36%, 95% CI 34–38 versus 26%, 95% CI 24–27, p<0.001). The 70–79-year-old group adhered to PAP therapy equally well as the younger age groups with a mean PAP use of 5.59 h·day−1 (95% CI 5.44–5.75). PAP adherence did not differ between clinical phenotypes based on subjective daytime sleepiness and sleep complaints suggestive of insomnia in the oldest age group. A higher score on the Clinical Global Impression Severity (CGI-S) scale predicted poorer PAP adherence. Conclusion The elderly patient group was less obese, less sleepy, had more insomnia symptoms and less severe OSA, but were rated to be more ill compared with the middle-aged patients. Elderly patients with OSA adhered to PAP therapy equally well as middle-aged patients. Low global functioning (measured by CGI-S) in the elderly patient predicted poorer PAP adherence.http://openres.ersjournals.com/content/9/3/00506-2022.full |
| spellingShingle | Aino Lammintausta Ulla Anttalainen Özen K. Basoglu Maria R. Bonsignore Haralampos Gouveris Ludger Grote Jan Hedner Ondrej Ludka Stefan Mihaicuta Athanasia Pataka Georgia Trakada Mafalda van Zeller Tarja Saaresranta Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort ERJ Open Research |
| title | Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort |
| title_full | Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort |
| title_fullStr | Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort |
| title_full_unstemmed | Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort |
| title_short | Clinical characteristics and positive airway pressure adherence among elderly European sleep apnoea patients from the ESADA cohort |
| title_sort | clinical characteristics and positive airway pressure adherence among elderly european sleep apnoea patients from the esada cohort |
| url | http://openres.ersjournals.com/content/9/3/00506-2022.full |
| work_keys_str_mv | AT ainolammintausta clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT ullaanttalainen clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT ozenkbasoglu clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT mariarbonsignore clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT haralamposgouveris clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT ludgergrote clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT janhedner clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT ondrejludka clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT stefanmihaicuta clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT athanasiapataka clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT georgiatrakada clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT mafaldavanzeller clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort AT tarjasaaresranta clinicalcharacteristicsandpositiveairwaypressureadherenceamongelderlyeuropeansleepapnoeapatientsfromtheesadacohort |