Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study
ABSTRACT CONTEXT AND OBJECTIVE : Adherence to medication is a key issue relating to outcomes from transplantation and it is influenced by several factors, such as stress and coping strategies. However, these factors have been poorly explored. We aimed to compare stress and coping strategies between...
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
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| Series: | São Paulo Medical Journal |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802016000400292&lng=en&tlng=en |
| _version_ | 1819277966809497600 |
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| author | Daniela Cristina Sampaio de Brito Elisa Oliveira Marsicano Fabiane Rossi dos Santos Grincenkov Fernando Antônio Basile Colugnati Giancarlo Lucchetti Helady Sanders-Pinheiro |
| author_facet | Daniela Cristina Sampaio de Brito Elisa Oliveira Marsicano Fabiane Rossi dos Santos Grincenkov Fernando Antônio Basile Colugnati Giancarlo Lucchetti Helady Sanders-Pinheiro |
| author_sort | Daniela Cristina Sampaio de Brito |
| collection | DOAJ |
| description | ABSTRACT CONTEXT AND OBJECTIVE : Adherence to medication is a key issue relating to outcomes from transplantation and it is influenced by several factors, such as stress and coping strategies. However, these factors have been poorly explored. We aimed to compare stress and coping strategies between adherent and nonadherent renal transplant recipients who were receiving immunosuppression. DESIGN AND SETTING : We conducted a comparative, cross-sectional and observational study at a university-based transplantation clinic in Juiz de Fora, Brazil. METHODS :Fifty patients were recruited and classified as adherent or nonadherent following administration of the Basel Assessment of Adherence to Immunosuppressive Medications Scale. Stress was evaluated using the Lipp Stress Symptom Inventory for Adults and coping strategies were assessed using the Ways of Coping Scale. RESULTS : The study included 25 nonadherent patients and 25 controls with a mean age of 44.1 ± 12.8 years and median post-transplantation time of 71.8 months. Stress was present in 50% of the patients. Through simple logistic regression, nonadherence was correlated with palliative coping (OR 3.4; CI: 1.02-11.47; P < 0.05) and had a marginal trend toward significance with more advanced phases of stress (OR 4.7; CI: 0.99-22.51; P = 0.053). CONCLUSION :Stress and coping strategies may have implications for understanding and managing nonadherent behavior among transplantation patients and should be considered among the strategies for reducing nonadherence. |
| first_indexed | 2024-12-24T00:04:31Z |
| format | Article |
| id | doaj.art-3036351a355e4d91b8f413667a2a4c70 |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-12-24T00:04:31Z |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-3036351a355e4d91b8f413667a2a4c702022-12-21T17:25:02ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-9460134429229910.1590/1516-3180.2015.01071008S1516-31802016000400292Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative studyDaniela Cristina Sampaio de BritoElisa Oliveira MarsicanoFabiane Rossi dos Santos GrincenkovFernando Antônio Basile ColugnatiGiancarlo LucchettiHelady Sanders-PinheiroABSTRACT CONTEXT AND OBJECTIVE : Adherence to medication is a key issue relating to outcomes from transplantation and it is influenced by several factors, such as stress and coping strategies. However, these factors have been poorly explored. We aimed to compare stress and coping strategies between adherent and nonadherent renal transplant recipients who were receiving immunosuppression. DESIGN AND SETTING : We conducted a comparative, cross-sectional and observational study at a university-based transplantation clinic in Juiz de Fora, Brazil. METHODS :Fifty patients were recruited and classified as adherent or nonadherent following administration of the Basel Assessment of Adherence to Immunosuppressive Medications Scale. Stress was evaluated using the Lipp Stress Symptom Inventory for Adults and coping strategies were assessed using the Ways of Coping Scale. RESULTS : The study included 25 nonadherent patients and 25 controls with a mean age of 44.1 ± 12.8 years and median post-transplantation time of 71.8 months. Stress was present in 50% of the patients. Through simple logistic regression, nonadherence was correlated with palliative coping (OR 3.4; CI: 1.02-11.47; P < 0.05) and had a marginal trend toward significance with more advanced phases of stress (OR 4.7; CI: 0.99-22.51; P = 0.053). CONCLUSION :Stress and coping strategies may have implications for understanding and managing nonadherent behavior among transplantation patients and should be considered among the strategies for reducing nonadherence.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802016000400292&lng=en&tlng=enStress, psychologicalAdaptation, psychologicalMedication adherencePatient complianceKidney transplantation |
| spellingShingle | Daniela Cristina Sampaio de Brito Elisa Oliveira Marsicano Fabiane Rossi dos Santos Grincenkov Fernando Antônio Basile Colugnati Giancarlo Lucchetti Helady Sanders-Pinheiro Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study São Paulo Medical Journal Stress, psychological Adaptation, psychological Medication adherence Patient compliance Kidney transplantation |
| title | Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study |
| title_full | Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study |
| title_fullStr | Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study |
| title_full_unstemmed | Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study |
| title_short | Stress, coping and adherence to immunosuppressive medications in kidney transplantation: a comparative study |
| title_sort | stress coping and adherence to immunosuppressive medications in kidney transplantation a comparative study |
| topic | Stress, psychological Adaptation, psychological Medication adherence Patient compliance Kidney transplantation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802016000400292&lng=en&tlng=en |
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