Research progress of drug resistance mechanisms to temozolomide in glioblastoma: A narrative review

Research progress of drug resistance mechanisms to temozolomide in glioblastoma: A narrative review

Glioblastoma multiforme (GBM) is the most common malignant tumor in the adult central nervous system, and surgery combined with radiotherapy and chemotherapy represents the main treatment regimens. Temozolomide (TMZ) is currently the first-line chemotherapeutic agent used in GBM therapy and is widel...

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Bibliographic Details
Main Author: Allen Lu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Glioma
Subjects:
dna damage
glioblastoma
glioma stem cells
resistance mechanisms
temozolomide
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2022;volume=5;issue=3;spage=81;epage=86;aulast=Lu

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