Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism
In this article, we discuss difficulties in parathyroid localization modalities in diagnosis of primary hyperparathyroidism. Most often, superior parathyroid glands are located on the posteromedial surface of the right and left lobes of the thyroid gland, however, they also could be found at the car...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Endocrinology Research Centre
2018-04-01
|
| Series: | Остеопороз и остеопатии |
| Subjects: | |
| Online Access: | https://osteo-endojournals.ru/osteo/article/viewFile/9607/7210 |
| _version_ | 1818448342344007680 |
|---|---|
| author | Dmitry G. Beltsevich Valeriy V. Voskoboynikov Camila M. Klycheva Anna A. Roslyakova Daria O. Ladygina |
| author_facet | Dmitry G. Beltsevich Valeriy V. Voskoboynikov Camila M. Klycheva Anna A. Roslyakova Daria O. Ladygina |
| author_sort | Dmitry G. Beltsevich |
| collection | DOAJ |
| description | In this article, we discuss difficulties in parathyroid localization modalities in diagnosis of primary hyperparathyroidism. Most often, superior parathyroid glands are located on the posteromedial surface of the right and left lobes of the thyroid gland, however, they also could be found at the carotid bifurcation, behind pharynx and esophagus, as well as inside thyroid gland. Location of the inferior parathyroid glands is more variable: on the side or back surface, or below the lower pole of the thyroid gland, as well as in thymus, posterior or anterior mediastinum, or inside thyroid. Localization modalities of primary hyperparathyroidism are based on neck ultrasonography, scintigraphy with sestamibi, computed tomography of neck and mediastinum. In cases with combination of multinodal goitre and an intrathyroid location of the parathyroid gland, there might be additional difficulties in verification of various patterns (thyroid nodules or parathyroid glands). In this article, we present two clinical cases of intrathyroid location of parathyroid glands. The algorithm of parathyroid adenoma localization is shown. Determination of PTH level in washing liquid after fine-needle aspiration biopsy from necessary punctures of the nodule formations, which can be either intrathyroid parathyroid glands or thyroid nodules, can also help to avoid diagnostic mistakes. |
| first_indexed | 2024-12-14T20:17:59Z |
| format | Article |
| id | doaj.art-303a2eda976a4209b37ca5ac7cb42e04 |
| institution | Directory Open Access Journal |
| issn | 2072-2680 2311-0716 |
| language | English |
| last_indexed | 2024-12-14T20:17:59Z |
| publishDate | 2018-04-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Остеопороз и остеопатии |
| spelling | doaj.art-303a2eda976a4209b37ca5ac7cb42e042022-12-21T22:48:48ZengEndocrinology Research CentreОстеопороз и остеопатии2072-26802311-07162018-04-0120310811310.14341/osteo20173108-1138454Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidismDmitry G. Beltsevich0Valeriy V. Voskoboynikov1Camila M. Klycheva2Anna A. Roslyakova3Daria O. Ladygina4Endocrinology Research CentreEndocrinology Research CentreEndocrinology Research CentreEndocrinology Research CentreCentral Clinical Hospital of the Management Affair of President Russian FederationIn this article, we discuss difficulties in parathyroid localization modalities in diagnosis of primary hyperparathyroidism. Most often, superior parathyroid glands are located on the posteromedial surface of the right and left lobes of the thyroid gland, however, they also could be found at the carotid bifurcation, behind pharynx and esophagus, as well as inside thyroid gland. Location of the inferior parathyroid glands is more variable: on the side or back surface, or below the lower pole of the thyroid gland, as well as in thymus, posterior or anterior mediastinum, or inside thyroid. Localization modalities of primary hyperparathyroidism are based on neck ultrasonography, scintigraphy with sestamibi, computed tomography of neck and mediastinum. In cases with combination of multinodal goitre and an intrathyroid location of the parathyroid gland, there might be additional difficulties in verification of various patterns (thyroid nodules or parathyroid glands). In this article, we present two clinical cases of intrathyroid location of parathyroid glands. The algorithm of parathyroid adenoma localization is shown. Determination of PTH level in washing liquid after fine-needle aspiration biopsy from necessary punctures of the nodule formations, which can be either intrathyroid parathyroid glands or thyroid nodules, can also help to avoid diagnostic mistakes.https://osteo-endojournals.ru/osteo/article/viewFile/9607/7210primary hyperparathyroidismphptfine-needle aspiration biopsypth-fnabintrathyroidal parathyroid glandparathyroid hormonepthcase report |
| spellingShingle | Dmitry G. Beltsevich Valeriy V. Voskoboynikov Camila M. Klycheva Anna A. Roslyakova Daria O. Ladygina Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism Остеопороз и остеопатии primary hyperparathyroidism phpt fine-needle aspiration biopsy pth-fnab intrathyroidal parathyroid gland parathyroid hormone pth case report |
| title | Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism |
| title_full | Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism |
| title_fullStr | Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism |
| title_full_unstemmed | Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism |
| title_short | Role of parathyroid hormone measurement in fine-needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism |
| title_sort | role of parathyroid hormone measurement in fine needle aspiration biopsy washout in diagnosis and treatment of primary hyperparathyroidism |
| topic | primary hyperparathyroidism phpt fine-needle aspiration biopsy pth-fnab intrathyroidal parathyroid gland parathyroid hormone pth case report |
| url | https://osteo-endojournals.ru/osteo/article/viewFile/9607/7210 |
| work_keys_str_mv | AT dmitrygbeltsevich roleofparathyroidhormonemeasurementinfineneedleaspirationbiopsywashoutindiagnosisandtreatmentofprimaryhyperparathyroidism AT valeriyvvoskoboynikov roleofparathyroidhormonemeasurementinfineneedleaspirationbiopsywashoutindiagnosisandtreatmentofprimaryhyperparathyroidism AT camilamklycheva roleofparathyroidhormonemeasurementinfineneedleaspirationbiopsywashoutindiagnosisandtreatmentofprimaryhyperparathyroidism AT annaaroslyakova roleofparathyroidhormonemeasurementinfineneedleaspirationbiopsywashoutindiagnosisandtreatmentofprimaryhyperparathyroidism AT dariaoladygina roleofparathyroidhormonemeasurementinfineneedleaspirationbiopsywashoutindiagnosisandtreatmentofprimaryhyperparathyroidism |