More Human BM-MSC With Similar Subpopulation Composition and Functional Characteristics Can Be Produced With a GMP-Compatible Fabric Filter System Compared to Density Gradient Technique

More Human BM-MSC With Similar Subpopulation Composition and Functional Characteristics Can Be Produced With a GMP-Compatible Fabric Filter System Compared to Density Gradient Technique

BackgroundMesenchymal stromal cells (MSCs), multipotent progenitors that can be isolated from a variety of different tissues, are becoming increasingly important as cell therapeutics targeting immunopathologies and tissue regeneration. Current protocols for MSC isolation from bone marrow (BM) rely o...

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Bibliographic Details
Main Authors: Gabriele Spohn, Anne-Sophie Witte, Anja Kretschmer, Erhard Seifried, Richard Schäfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mesenchymal stromal cell
production
heterogeneity
subpopulation
function
GMP
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.638798/full

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