Stressed neuronal cells can recover from profound membrane blebbing, nuclear condensation and mitochondrial fragmentation, but not from cytochrome c release
Abstract Loss of neurons in chronic neurodegenerative diseases may occur over a period of many years. Once initiated, neuronal cell death is accompanied by distinct phenotypic changes including cell shrinkage, neurite retraction, mitochondrial fragmentation, nuclear condensation, membrane blebbing a...
Main Authors: | Wenting You, Tao Zhou, Kèvin Knoops, Tos T. J. M. Berendschot, Marc A. M. J. van Zandvoort, Wilfred T. V. Germeraad, Birke Benedikter, Carroll A. B. Webers, Chris P. M. Reutelingsperger, Theo G. M. F. Gorgels |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-38210-w |
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