Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection

Outpatient antibiotics are most frequently prescribed for upper respiratory tract infection (URI); however, most such prescriptions are inappropriate. We aimed to determine the effect of an electronic clinical pathway on the rates of overall and rational prescription of antibiotics in patients with...

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Main Authors: Wantin Sribenjalux, Nattawat Larbsida, Sittichai Khamsai, Benjaphol Panyapornsakul, Phitphiboon Deawtrakulchai, Atibordee Meesing
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/12/1479
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author Wantin Sribenjalux
Nattawat Larbsida
Sittichai Khamsai
Benjaphol Panyapornsakul
Phitphiboon Deawtrakulchai
Atibordee Meesing
author_facet Wantin Sribenjalux
Nattawat Larbsida
Sittichai Khamsai
Benjaphol Panyapornsakul
Phitphiboon Deawtrakulchai
Atibordee Meesing
author_sort Wantin Sribenjalux
collection DOAJ
description Outpatient antibiotics are most frequently prescribed for upper respiratory tract infection (URI); however, most such prescriptions are inappropriate. We aimed to determine the effect of an electronic clinical pathway on the rates of overall and rational prescription of antibiotics in patients with URI. A pilot quasi-experimental study was conducted in a university hospital and two of its nearby primary care units (PCU) in northeast Thailand from June to September 2020. Clinical pathway pop-up windows were inserted into the hospital’s computer-based prescription system. Care providers were required to check the appropriate boxes before they were able to prescribe amoxicillin or co-amoxiclav. We examined a total of 675 visits to the outpatient department due to URI at three points in time: pre-intervention, immediately post-intervention, and 6 weeks post-intervention. Patients in the latter group tended to be younger and visits were more likely to be general practitioner-related and to the student PCU than in the other two groups. In addition, the rate of antibiotic prescription was significantly lower at 6 weeks after intervention than at either of the other time periods (32.0% vs 53.8% pre-intervention and 46.2% immediately post-intervention; <i>p</i> < 0.001), and the proportion of rational antibiotic prescriptions increased significantly after implementation. Antibiotic prescription rates were lower at the community primary care unit and higher when the physician was a resident or a family doctor. The deployment of an electronic clinical pathway reduced the rate of unnecessary antibiotic prescriptions. The effect was greater at 6 weeks post-implementation. However, discrepancy of patients’ baseline characteristics may have skewed the findings.
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spelling doaj.art-303e4e6f193a4f95b8cc7d3e4be061722023-11-23T03:30:29ZengMDPI AGAntibiotics2079-63822021-12-011012147910.3390/antibiotics10121479Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract InfectionWantin Sribenjalux0Nattawat Larbsida1Sittichai Khamsai2Benjaphol Panyapornsakul3Phitphiboon Deawtrakulchai4Atibordee Meesing5Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, ThailandOutpatient antibiotics are most frequently prescribed for upper respiratory tract infection (URI); however, most such prescriptions are inappropriate. We aimed to determine the effect of an electronic clinical pathway on the rates of overall and rational prescription of antibiotics in patients with URI. A pilot quasi-experimental study was conducted in a university hospital and two of its nearby primary care units (PCU) in northeast Thailand from June to September 2020. Clinical pathway pop-up windows were inserted into the hospital’s computer-based prescription system. Care providers were required to check the appropriate boxes before they were able to prescribe amoxicillin or co-amoxiclav. We examined a total of 675 visits to the outpatient department due to URI at three points in time: pre-intervention, immediately post-intervention, and 6 weeks post-intervention. Patients in the latter group tended to be younger and visits were more likely to be general practitioner-related and to the student PCU than in the other two groups. In addition, the rate of antibiotic prescription was significantly lower at 6 weeks after intervention than at either of the other time periods (32.0% vs 53.8% pre-intervention and 46.2% immediately post-intervention; <i>p</i> < 0.001), and the proportion of rational antibiotic prescriptions increased significantly after implementation. Antibiotic prescription rates were lower at the community primary care unit and higher when the physician was a resident or a family doctor. The deployment of an electronic clinical pathway reduced the rate of unnecessary antibiotic prescriptions. The effect was greater at 6 weeks post-implementation. However, discrepancy of patients’ baseline characteristics may have skewed the findings.https://www.mdpi.com/2079-6382/10/12/1479antibiotic stewardshipantibiotic prescriptionclinical pathwaypop-up windowupper respiratory tract infection
spellingShingle Wantin Sribenjalux
Nattawat Larbsida
Sittichai Khamsai
Benjaphol Panyapornsakul
Phitphiboon Deawtrakulchai
Atibordee Meesing
Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection
Antibiotics
antibiotic stewardship
antibiotic prescription
clinical pathway
pop-up window
upper respiratory tract infection
title Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection
title_full Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection
title_fullStr Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection
title_full_unstemmed Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection
title_short Insertion of a Clinical Pathway Pop-Up Window into a Computer-Based Prescription System: A Method to Promote Antibiotic Stewardship in Upper Respiratory Tract Infection
title_sort insertion of a clinical pathway pop up window into a computer based prescription system a method to promote antibiotic stewardship in upper respiratory tract infection
topic antibiotic stewardship
antibiotic prescription
clinical pathway
pop-up window
upper respiratory tract infection
url https://www.mdpi.com/2079-6382/10/12/1479
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