Statistical Methods in the Study of Protein Binding and Its Relationship to Drug Bioavailability in Breast Milk

Statistical Methods in the Study of Protein Binding and Its Relationship to Drug Bioavailability in Breast Milk

Protein binding (PB) is indicated as the factor most severely limiting distribution in the organism, reducing the bioavailability of the drug, but also minimizing the penetration of xenobiotics into the fetus or the body of a breastfed child. Therefore, PB is an important aspect to be analyzed and m...

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Bibliographic Details
Main Authors: Karolina Wanat, Elżbieta Brzezińska
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
protein binding
breast milk
M/P ratio
statistical modeling
molecular descriptors
chromatographic descriptors
Online Access:https://www.mdpi.com/1420-3049/27/11/3441

Internet

https://www.mdpi.com/1420-3049/27/11/3441

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