Novelties on amoebiasis: A neglected tropical disease

In accordance with the 1997 documents of the World Health Organization (WHO), amoebiasis is defined as the infection by the protozoan parasite Entamoeba histolytica with or without clinical manifestations. The only known natural host of E. histolytica is the human with the large intestine as major t...

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Main Authors: Cecilia Ximénez, Patricia Morán, Liliana Rojas, Alicia Valadez, Alejandro Gómez, Manuel Ramiro, René Cerritos, Enrique González, Eric Hernández, Partida Oswaldo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Global Infectious Diseases
Subjects:
Online Access:http://www.jgid.org/article.asp?issn=0974-777X;year=2011;volume=3;issue=2;spage=166;epage=174;aulast=Ximénez
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author Cecilia Ximénez
Patricia Morán
Liliana Rojas
Alicia Valadez
Alejandro Gómez
Manuel Ramiro
René Cerritos
Enrique González
Eric Hernández
Partida Oswaldo
author_facet Cecilia Ximénez
Patricia Morán
Liliana Rojas
Alicia Valadez
Alejandro Gómez
Manuel Ramiro
René Cerritos
Enrique González
Eric Hernández
Partida Oswaldo
author_sort Cecilia Ximénez
collection DOAJ
description In accordance with the 1997 documents of the World Health Organization (WHO), amoebiasis is defined as the infection by the protozoan parasite Entamoeba histolytica with or without clinical manifestations. The only known natural host of E. histolytica is the human with the large intestine as major target organ. This parasite has a very simple life cycle in which the infective form is the cyst, considered a resistant form of parasite: The asymptomatic cyst passers and the intestinal amoebiasis patients are the transmitters; they excrete cysts in their feces, which can contaminate food and water sources. E. histolytica sensu stricto is the potentially pathogenic species and E. dispar is a commensal non-pathogenic Entamoeba. Both species are biochemical, immunological and genetically distinct. The knowledge of both species with different pathogenic phenotypes comes from a large scientific debate during the second half of the 20 th century, which gave place to the rapid development of diagnostics technology based on molecular and immunological strategies. During the last ten years, knowledge of the new epidemiology of amoebiasis in different geographic endemic and non-endemic areas has been obtained by applying mostly molecular techniques. In the present work we highlight novelties on human infection and the disease that can help the general physician from both endemic and non-endemic countries in their medical practice, particularly, now that emigration is undoubtedly a global phenomenon that is modifying the previous geography of infectious diseases worldwide.
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spelling doaj.art-3042b8b053c1431a980e65dee1e4bd2c2022-12-21T23:33:10ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2011-01-013216617410.4103/0974-777X.81695Novelties on amoebiasis: A neglected tropical diseaseCecilia XiménezPatricia MoránLiliana RojasAlicia ValadezAlejandro GómezManuel RamiroRené CerritosEnrique GonzálezEric HernándezPartida OswaldoIn accordance with the 1997 documents of the World Health Organization (WHO), amoebiasis is defined as the infection by the protozoan parasite Entamoeba histolytica with or without clinical manifestations. The only known natural host of E. histolytica is the human with the large intestine as major target organ. This parasite has a very simple life cycle in which the infective form is the cyst, considered a resistant form of parasite: The asymptomatic cyst passers and the intestinal amoebiasis patients are the transmitters; they excrete cysts in their feces, which can contaminate food and water sources. E. histolytica sensu stricto is the potentially pathogenic species and E. dispar is a commensal non-pathogenic Entamoeba. Both species are biochemical, immunological and genetically distinct. The knowledge of both species with different pathogenic phenotypes comes from a large scientific debate during the second half of the 20 th century, which gave place to the rapid development of diagnostics technology based on molecular and immunological strategies. During the last ten years, knowledge of the new epidemiology of amoebiasis in different geographic endemic and non-endemic areas has been obtained by applying mostly molecular techniques. In the present work we highlight novelties on human infection and the disease that can help the general physician from both endemic and non-endemic countries in their medical practice, particularly, now that emigration is undoubtedly a global phenomenon that is modifying the previous geography of infectious diseases worldwide.http://www.jgid.org/article.asp?issn=0974-777X;year=2011;volume=3;issue=2;spage=166;epage=174;aulast=XiménezAmoebiasisDiagnosisTreatment
spellingShingle Cecilia Ximénez
Patricia Morán
Liliana Rojas
Alicia Valadez
Alejandro Gómez
Manuel Ramiro
René Cerritos
Enrique González
Eric Hernández
Partida Oswaldo
Novelties on amoebiasis: A neglected tropical disease
Journal of Global Infectious Diseases
Amoebiasis
Diagnosis
Treatment
title Novelties on amoebiasis: A neglected tropical disease
title_full Novelties on amoebiasis: A neglected tropical disease
title_fullStr Novelties on amoebiasis: A neglected tropical disease
title_full_unstemmed Novelties on amoebiasis: A neglected tropical disease
title_short Novelties on amoebiasis: A neglected tropical disease
title_sort novelties on amoebiasis a neglected tropical disease
topic Amoebiasis
Diagnosis
Treatment
url http://www.jgid.org/article.asp?issn=0974-777X;year=2011;volume=3;issue=2;spage=166;epage=174;aulast=Ximénez
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