Avicularin alleviates osteoporosis-induced implant loosening by attenuating macrophage M1 polarization via its inhibitory effect on the activation of NF-κB

Avicularin alleviates osteoporosis-induced implant loosening by attenuating macrophage M1 polarization via its inhibitory effect on the activation of NF-κB

Currently, the failure rate for internal fixation in patients with osteoporosis can be reduced by antiosteoporosis therapy alone. However, the administration of anti-osteoporotic drugs is not a complete solution. Therefore, it is necessary to investigate other causes of surgical failure, such as inf...

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Bibliographic Details
Main Authors:	Yunshang Yang, Dong Sheng, Jiandong Shi, Long Xiao, Zhifang Wang, Zhengyu Yin, Qi Zhuang, Shuangshuang Chen, Yajun Li, Yong Gu, Jie Zhu, Dechun Geng, Zhirong Wang
Format:	Article
Language:	English
Published:	Elsevier 2023-02-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Implant instability Osteoporosis Avicularin Inflammatory NF-κB
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332222015025

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