The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials
BackgroundThe current evidence on the effect of Sumac consumption on cardiovascular parameters has produced controversial findings.MethodsWe systematically searched several databases, including PubMed-Medline, SCOPUS, and ISI Web of Science, to find eligible studies until January 2023. Meta-analysis...
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2024.1305024/full |
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| author | Amirhosein Jafarpour Saeedeh Jalali Masoumeh Akhlaghi Manoochehr Amin Amlashi |
| author_facet | Amirhosein Jafarpour Saeedeh Jalali Masoumeh Akhlaghi Manoochehr Amin Amlashi |
| author_sort | Amirhosein Jafarpour |
| collection | DOAJ |
| description | BackgroundThe current evidence on the effect of Sumac consumption on cardiovascular parameters has produced controversial findings.MethodsWe systematically searched several databases, including PubMed-Medline, SCOPUS, and ISI Web of Science, to find eligible studies until January 2023. Meta-analysis to calculated the weighted mean difference (WMD) and 95 %CI, Sub-group meta-analysis and meta-regression analysis were conducted throughout the study.Results16 randomized controlled trials comprising a total number of 1,225 participants were included. The results of meta-analysis revealed that Sumac significantly affected low-density lipoprotein (WMD: −8.66 mg/dL; 95% CI: −14.2, −3.12), high-density lipoprotein (WMD: 3.15 mg/dL; 1.99,4.31), triglycerides (WMD: −11.96 mg/dL; −19.44, −4.48), fasting blood glucose (WMD: −4.15 mg/dL; −7.31, −0.98), insulin (WMD: −1.72; −3.18, −0.25), homeostasis model assessment of insulin resistance (HOMA-IR; WMD: −0.61; −1.22, −0.01), and anthropometric indices (p < 0.05). Moreover, the results significantly reduced total cholesterol when the intervention duration was ≥12 weeks (WMD: −8.58 mg/dL; −16.8, −0.37).ConclusionThese findings suggest that Sumac is potentially an effective complementary intervention to improve cardiometabolic parameters. Thus, patients could utilize Sumac as part of their diet to improve their overall cardiometabolic status. |
| first_indexed | 2024-03-08T09:41:32Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-08T09:41:32Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-30438c5b146c4736ae91a44d20cb85e82024-01-30T04:19:57ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2024-01-011110.3389/fnut.2024.13050241305024The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trialsAmirhosein Jafarpour0Saeedeh Jalali1Masoumeh Akhlaghi2Manoochehr Amin Amlashi3Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, IranBackgroundThe current evidence on the effect of Sumac consumption on cardiovascular parameters has produced controversial findings.MethodsWe systematically searched several databases, including PubMed-Medline, SCOPUS, and ISI Web of Science, to find eligible studies until January 2023. Meta-analysis to calculated the weighted mean difference (WMD) and 95 %CI, Sub-group meta-analysis and meta-regression analysis were conducted throughout the study.Results16 randomized controlled trials comprising a total number of 1,225 participants were included. The results of meta-analysis revealed that Sumac significantly affected low-density lipoprotein (WMD: −8.66 mg/dL; 95% CI: −14.2, −3.12), high-density lipoprotein (WMD: 3.15 mg/dL; 1.99,4.31), triglycerides (WMD: −11.96 mg/dL; −19.44, −4.48), fasting blood glucose (WMD: −4.15 mg/dL; −7.31, −0.98), insulin (WMD: −1.72; −3.18, −0.25), homeostasis model assessment of insulin resistance (HOMA-IR; WMD: −0.61; −1.22, −0.01), and anthropometric indices (p < 0.05). Moreover, the results significantly reduced total cholesterol when the intervention duration was ≥12 weeks (WMD: −8.58 mg/dL; −16.8, −0.37).ConclusionThese findings suggest that Sumac is potentially an effective complementary intervention to improve cardiometabolic parameters. Thus, patients could utilize Sumac as part of their diet to improve their overall cardiometabolic status.https://www.frontiersin.org/articles/10.3389/fnut.2024.1305024/fullSumaclipid profileanthropometric indicesglycemic indicesblood pressurecardiometabolic indices |
| spellingShingle | Amirhosein Jafarpour Saeedeh Jalali Masoumeh Akhlaghi Manoochehr Amin Amlashi The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials Frontiers in Nutrition Sumac lipid profile anthropometric indices glycemic indices blood pressure cardiometabolic indices |
| title | The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials |
| title_full | The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials |
| title_short | The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials |
| title_sort | effect of sumac on cardiometabolic parameters in adults a systematic review and meta analysis of randomized controlled trials |
| topic | Sumac lipid profile anthropometric indices glycemic indices blood pressure cardiometabolic indices |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2024.1305024/full |
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